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TP53 BRCA1 CRISPR single-cell cancer

Morikawa(Teppei),Baba(Yoshifumi),Yamauchi(... Clin Cancer Res 2011-07-22

...PIK3CA mutations.,Among the 724 tumors, 131 (18%) showed high-level p-STAT3 expression (p-STAT3-high), 244 (34%) showed ...

Saridaki(Zacharenia),Tzardi(Maria),Papadak... PLoS One 2011-08-02

To investigate the predictive significance of KRAS, BRAF, PIK3CA mutational status, AREG- EREG mRNA expression, PTEN pro...

Ludovini(Vienna),Bianconi(Fortunato),Pisto... J Thorac Oncol 2011-09-27

...PIK3CA mutation in 4.1%, and KRAS mutation in 6.7%. PIK3CA mutation correlated with shorter median time to progression (...

Su(Zengliu),Dias-Santagata(Dora),Duke(Mark... J Mol Diagn 2011-11-08

...PIK3CA, and PTEN) and a PCR-based sizing assay that assesses for EGFR exon 19 deletions, EGFR exon 20 insertions, and HE...

Gonzalez-Bosquet(Jesus),Calcei(Jacob),Wei(... PLoS One 2011-08-02

...PIK3CA, ERBB2, KRAS, TP53, EGFR, BRAF, GATA3, and FGFR3. Bi-directional sequencing analysis was used to determine the ac...

Rudd(Meghan L),Price(Jessica C),Fogoros(Sa... Clin Cancer Res 2011-07-22

...PIK3CA mutations were detected in 52.4% of 42 EECs and 33.3% of 66 NEECs. Half (29 of 58) of all nonsynonymous PIK3CA mu...

Gounaris(Ioannis),Charnock-Jones(D Stephen... J Pathol 2011-11-02

...PIK3CA have been described in a substantial fraction of cases of ovarian clear cell carcinoma, yet the paper by Yamamoto...

Naumann(R Wendel) Gynecol Oncol 2011-12-07

...PIK3CA, and KRAS. Deregulation of the pathway has been associated with resistance to hormonal therapy and chemotherapy. ...

Weidlich(S),Walsh(K),Crowther(D),Burczynsk... Br J Cancer 2011-09-09

...PIK3CA (phosphoinositide-3-kinase) may also influence cetuximab response, highlighting the need for a sensitive, accurat...

Janku(Filip),Garrido-Laguna(Ignacio),Petru... J Thorac Oncol 2011-12-19

...PIK3CA), serine/threonine-protein kinase B-raf (BRAF), and insulin-like growth factor 1 receptor (IGF-1R). Some target-d...

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