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TP53 BRCA1 CRISPR single-cell cancer

Vorkas(Panagiotis A),Poumpouridou(Nikoleta... J Mol Diagn 2011-01-13

...PIK3CA gene that is based on a combination of PCR and HRMA. The PIK3CA HRMA assay was evaluated by performing repeatabil...

Herreros-Villanueva(Marta),Gomez-Manero(No... Mol Biol Rep 2011-05-26

...PIK3CA status were analyzed by real-time PCR in all patients. PIK3CA mutations were present in 8.22% of wild type KRAS a...

Slomovitz(Brian M),Lu(Karen H),Johnston(Ta... Cancer 2011-02-15

...PIK3CA, are the most common mutations in endometrial carcinoma (EC). Loss of PTEN or activation of PIK3CA results in con...

Samuels(Yardena),Waldman(Todd) Curr Top Microbiol Immunol 2011-01-03

The involvement of the PIK3CA gene product p110α, the catalytic subunit of phosphatidylinositol 3-kinase (PI3K), in huma...

Berg(Marianne),Danielsen(Stine A),Ahlquist... PLoS One 2011-04-27

...PIK3CA (4%), PTEN (14%) and TP53 (51%). In patients younger than 50 years (n = 45), PIK3CA mutations were not observed a...

Li(Guoqiang),Luo(Xiaodi),He(Jiaying),Zhu(Z... Clin Chem Lab Med 2011-05-27

DNA somatic mutations of EGFR, KRAS, BRAF and PIK3CA in the epidermal growth factor receptor (EGFR) signaling pathway pl...

Ogino(Shuji),Chan(Andrew T),Fuchs(Charles ... Gut 2011-03-21

...PIK3CA affects intracellular signalling pathways and has been associated with CIMP and MSI. Traditional epidemiology res...

Kompier(Lucie C),Lurkin(Irene),van der Aa(... PLoS One 2011-04-27

...PIK3CA, and 26% for p53. FGFR3 mutations were mutually exclusive with RAS mutations (p = 0.001) and co-occurred with PIK...

Hafner(Christian),Toll(Agustí),Fernández-C... Proc Natl Acad Sci U S A 2011-01-05

...PIK3CA, KRAS, HRAS, EGFR, and AKT1 oncogenes but not in tumor suppressor genes TSC1 and PTEN. Despite the occurrence of ...

Rebucci(Magali),Peixoto(Paul),Dewitte(Amél... Int J Oncol 2011-05-24

...PIK3CA mutation. The treatment of CAL33 cells with PI3K inhibitor and cetuximab restores the inhibition of AKT phosphory...

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