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Inhibition of p53 induces invasion of serous borderline ovarian tumor cells b...

Cheng(J-C),Auersperg(N),Leung(P C K) Oncogene 2011-05-23

...PIK3CA levels and the increased activation of Akt. Conversely, in invasive LGC-derived MPSC1 cells, enhancing the levels...

Relationship between human oral lichen planus and oral squamous cell carcinom...

Giacomelli(Luca),Oluwadara(Oluwadayo),Chia... Bioinformation 2011-07-14

...PIK3CA, BIRC5, TP53 and CDKN1A in the malignant progression from OLP to OSCC. Moreover, these findings support the role ...

Detection of two novel mutations and relatively high incidence of H-RAS mutat...

Murugan(Avaniyapuram Kannan),Hong(Nguyen T... Oral Oncol 2011-03-16

...PIK3CA and PTEN gene mutations in Vietnamese oral cancer. We thus hypothesized that the RAS could be more likely activat...

Recent progess in phosphoinositide 3-kinases: oncogenic properties and progno...

Wu(Guojun) Curr Protein Pept Sci 2011-02-28

...PIK3CA mutations identified in human cancers. I also discuss the association of PIK3CA mutations with other genetic mark...

Molecular genotyping of papillary thyroid carcinoma follicular variant accord...

Rivera(Michael),Ricarte-Filho(Julio),Knauf... Mod Pathol 2011-01-03

...PIK3CA, AKT1 and other related genes. There was no difference in age, gender, tumor size and angioinvasion between encap...

PI3K as a target for therapy in haematological malignancies.

Khwaja(Asim) Curr Top Microbiol Immunol 2011-01-03

...PIK3CA and PTEN occur at a relatively low frequency in haematological malignancies, activation of PI3K signalling is oft...

Prognostic significance of CDKN2A (p16) promoter methylation and loss of expr...

Shima(Kaori),Nosho(Katsuhiko),Baba(Yoshifu... Int J Cancer 2011-02-01

...PIK3CA mutations; and expression of TP53 (p53), CTNNB1 (β-catenin), CDKN1A (p21), CDKN1B (p27), CCND1 (cyclin D1), FASN ...

Activation of the PI3K/AKT signalling pathway in non-melanoma skin cancer is ...

Hafner(Christian),Landthaler(Michael),Vogt... Exp Dermatol 2011-01-06

...PIK3CA and AKT1 mutations. PIK3CA hotspot mutations were analysed using a highly sensitive SNaPshot assay, and exon 4 of...

HER3 and downstream pathways are involved in colonization of brain metastases...

Da Silva(Leonard),Simpson(Peter T),Smart(C... Breast Cancer Res 2011-03-01

...PIK3CA. This paralleled the frequent activation of AKT and MAPK pathways. In particular, activation of the MAPK pathway ...

Clinicopathologic and molecular significance of phospho-Akt expression in ear...

Aleskandarany(Mohammed A),Rakha(Emad A),Ah... Breast Cancer Res Treat 2011-08-16

...PIK3CA and pAkt expression, with substantial proportions being PIK3CA⁻/pAkt⁺ or PIK3CA⁺/pAkt⁻. These four combinatorial ...

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