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Zhang(C),Zhang(J) Open Med (Wars) 2026-01-00

...PIK3CA as key hub genes enriched in the cerebral cortex and basal ganglia. Transcriptomic data confirmed differential ex...

Grollmann(H),Volz(B),Schroth(W),Bahlinger(... Geburtshilfe Frauenheilkd 2026-05-00

...PIK3CA mutation analysis via MassARRAY PIK3CA Breast Panel and digital droplet PCR. PIK3CA mutations were detected in 42...

Lin(J),Xu(H),Zhou(Y),Sa(Q),Wang(J),Xu(B) Adv Clin Exp Med 2026-06-00

...PIK3CA mutations correlated with worse PFS (HR = 2.12, 95% CI: 1.43-3.15, p = 0.002), whereas ERBB2 mutations showed no ...

Hong(S),Park(CS),Been(KW),Kang(S),Hong(J),... Biosensors (Basel) 2026-06-10

...PIK3CA H1047R mutations that were undetectable by conventional Sanger sequencing. To evaluate detection sensitivity, we ...

Jawad(H),Osonowo(O),Gilleard(JS),Thompson(... BMC Genomics 2026-06-16

...PIK3CA and AGXT duplications, with an enrichment of pathways associated with diabetic cardiomyopathy and prion disease. ...

Chen(L),Guo(J),Li(F),Gao(M),Li(R),Huang(Z)... Adv Sci (Weinh) 2026-08-00

...PIK3CA/AKT1/PTEN mutation(s), induced senescence selectively in FUCA2-high LUAD irrespective of PIK3CA/AKT1/PTEN/TP53 mu...

Sengul(I),Sengul(D),Akalin(C) Amino Acids 2026-06-16

...PIK3CA persist across both cohorts, the unique metabolic and immunological milieus confirm that these subtypes represent...

Nguyen(T),Mital(S) Expert Rev Pharmacoecon Out... 2026-07-00

Capivasertib was the first AKT inhibitor approved by the US FDA as a second-line treatment for PIK3CA/AKT1/PTEN-altered,...

Olwal(CO),Rathore(U),Makanani(SK),Kaushal(... iScience 2026-06-19

...PIK3CA-activating mutations through IRS1-PI3K-AKT pathway activation. Our findings highlight IRS1 and the PI3K pathway a...

Zhao(X),Wang(C),Ge(Y),Song(D),Guan(A),Hu(J... Anticancer Drugs 2026-05-25

...PIK3CA p.P471L missense mutation. A combination regimen of inavolisib (a selective PI3Kα inhibitor) and lenvatinib was i...