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Mechanistic analysis of a DNA damage-induced, PTEN-dependent size checkpoint ...

Kim(Jung-Sik),Xu(Xuehua),Li(Huifang),Solom... Mol Cell Biol 2011-08-23

...PIK3CA. Mutational analysis of PTEN and pharmacological inhibition of Akt revealed that modulation of Akt phosphorylatio...

Highly frequent promoter methylation and PIK3CA amplification in non-small ce...

Ji(Meiju),Guan(Haixia),Gao(Cuixia),Shi(Bin... BMC Cancer 2011-09-02

...PIK3CA amplification.,Our data showed highly frequent promoter methylation and PIK3CA amplification in Chinese NSCLC pop...

Type I collagen down-regulates E-cadherin expression by increasing PI3KCA in ...

Cheng(Jung-Chien),Leung(Peter C K) Cancer Lett 2011-05-17

...PIK3CA, which in turn contributed to the collagen I-induced down-regulation of E-cadherin by up-regulating its transcrip...

Targeting the phosphatidylinositol 3-kinase signaling pathway in breast cance...

Hernandez-Aya(Leonel F),Gonzalez-Angulo(An... Oncologist 2011-09-15

...PIK3CA and the loss of regulators of AKT including the tumor suppressor gene PTEN are mutations commonly found in breast...

Is the PIK3CA gene expression level in FNAB washouts equivalent to that in po...

Wojciechowska-Durczynska(Katarzyna),Krawcz... Neuro Endocrinol Lett 2011-07-12

...PIK3CA gene expression in PTC samples was not found.,The genetic analysis of overexpression of PIK3CA in FNAB washout sp...

Systematic review of pharmacogenetic testing for predicting clinical benefit ...

Lin(Jennifer S),Webber(Elizabeth M),Senger... Am J Cancer Res 2011-11-10

...PIK3CA, eight that studied PTEN expression, and five that studied AKT expression. The best evidence for BRAF, NRAS, and ...

New driver mutations in non-small-cell lung cancer.

Pao(William),Girard(Nicolas) Lancet Oncol 2011-03-14

...PIK3CA, AKT1, MAP2K1, and MET. The adoption of treatment tailored according to the genetic make-up of individual tumours...

Clear cell carcinoma of the ovary: a report from the first Ovarian Clear Cell...

Anglesio(Michael S),Carey(Mark S),Köbel(Ma... Gynecol Oncol 2011-06-14

...PIK3CA. Low-stage CCC appears to have a better outcome than stage matched HGSC, while the opposite is true for high-stag...

Detection of somatic mutations by high-resolution DNA melting (HRM) analysis ...

Gonzalez-Bosquet(Jesus),Calcei(Jacob),Wei(... PLoS One 2011-08-02

...PIK3CA, ERBB2, KRAS, TP53, EGFR, BRAF, GATA3, and FGFR3. Bi-directional sequencing analysis was used to determine the ac...

Sessile serrated adenoma with early neoplastic progression: a clinicopatholog...

Fujita(Kohei),Yamamoto(Hidetaka),Matsumoto... Am J Surg Pathol 2011-03-01

...PIK3CA in the development and progression of SSA. We analyzed 12 cases of SSA with neoplastic progression (SSAN), includ...

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