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TP53 BRCA1 CRISPR single-cell cancer

Kurman(Robert J),Shih(Ie-Ming) Hum Pathol 2011-09-14

...PIK3CA, ARID1A, and PPP2R1A, which target specific cell signaling pathways. Type I tumors rarely harbor TP53 mutations a...

Stransky(Nicolas),Egloff(Ann Marie),Tward(... Science 2011-09-07

...PIK3CA, and HRAS), our analysis revealed many genes not previously implicated in this malignancy. At least 30% of cases ...

Agrawal(Nishant),Frederick(Mitchell J),Pic... Science 2011-09-07

...PIK3CA, and HRAS, we identified mutations in FBXW7 and NOTCH1. Nearly 40% of the 28 mutations identified in NOTCH1 were ...

Liu(Dingxie),Xing(Joanna),Trink(Barry),Xin... Int J Cancer 2011-05-03

...PIK3CA H1047R(+)) and SW1376 (BRAF V600E(+)) was enhanced by combination with the mTOR inhibitor, temsirolimus. The PTEN...

Kondo(Norio),Tsukuda(Mamoru),Taguchi(Takah... Cancer Sci 2011-10-20

...PIK3CA, BRAF and PTEN. Furthermore, we evaluated cetuximab-mediated biological activities (antiproliferative effect by t...

Bygum(Anette),Fagerberg(Christina R),Clemm... BMC Med Genet 2011-09-06

...PIK3CA mutations have been implicated.,We report a female patient with a systemic keratinocytic nevus also involving the...

Lin(Ching-Hung),Lu(Yen-Shen),Huang(Chiun-S... J Clin Pathol 2011-10-19

...PIK3CA gene was carried out using direct sequencing analysis.,116 patients with a median follow-up duration of 62.7 mont...

Lin(Jen-Kou),Lin(An-Jen),Lin(Chun-Chi),Lan... J Surg Oncol 2011-11-29

...PIK3CA mutation was found. Of 26 wild-KRAS tumors, nine (34.6%) had a partial response to cetuximab: this was higher tha...

Bruin(S C),He(Y),Mikolajewska-Hanclich(I),... Br J Cancer 2011-09-09

...PIK3CA, KRAS, BRAF mutations, CIMP and microsatellite instability. The primary CRCs of the LM group had significantly hi...

Wang(Leiping),Zhang(Qunling),Zhang(Jian),S... BMC Cancer 2011-10-31

...PIK3CA mutations occur more frequently in elder patients for HER2-positive breast cancer. PIK3CA mutations and PTEN loss...

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