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TP53 BRCA1 CRISPR single-cell cancer

Samarnthai(Norasate),Hall(Kevin),Yeh(I-Tie... Obstet Gynecol Int 2011-07-14

...PIK3CA, KRAS, and beta-catenin, along with microsatellite instability, whereas type II endometrial carcinomas are charac...

Ogino(Shuji),Chan(Andrew T),Fuchs(Charles ... Gut 2011-03-21

...PIK3CA affects intracellular signalling pathways and has been associated with CIMP and MSI. Traditional epidemiology res...

Dupont Jensen(Jeanette),Laenkholm(Anne-Vib... Clin Cancer Res 2011-08-15

PIK3CA mutations are frequent in breast cancer and activate the PI3K/Akt pathway. Unexpectedly, PIK3CA mutation appears ...

Hafner(Christian),Toll(Agustí),Fernández-C... Proc Natl Acad Sci U S A 2011-01-05

...PIK3CA, KRAS, HRAS, EGFR, and AKT1 oncogenes but not in tumor suppressor genes TSC1 and PTEN. Despite the occurrence of ...

Kompier(Lucie C),Lurkin(Irene),van der Aa(... PLoS One 2011-04-27

...PIK3CA, and 26% for p53. FGFR3 mutations were mutually exclusive with RAS mutations (p = 0.001) and co-occurred with PIK...

Velho(Sérgia),Corso(Giovanni),Oliveíra(Car... Adv Cancer Res 2011-02-18

...PIK3CA, RASSF1A, and MLK3 genes) in MSI gastrointestinal carcinomas. Alterations in these genes characterize more than h...

Balschun(Katharina),Haag(Jochen),Wenke(Ann... J Mol Diagn 2011-10-17

...PIK3CA exon 20, and BRAF genotypes in synchronous and metachronous primary CRCs; in addition, we studied their available...

Drury(S C),Detre(S),Leary(A),Salter(J),Rei... Endocr Relat Cancer 2011-12-20

...PIK3CA mutations where possible. ER and PgR levels were significantly reduced at recurrence with 22 and 45%, respectivel...

Yamamoto(Sohei),Tsuda(Hitoshi),Takano(Masa... J Pathol 2011-11-02

...PIK3CA gene. In this study, we aimed to determine how these mutations contribute to tumour development of CCAs. Exons 9 ...

Laudański(Piotr),Kowalczuk(Oksana),Klasa-M... Folia Histochem Cytobiol 2011-10-27

...PIK3CA and BECN1. Confirmatory immunohistochemical detection was performed for a group of selected proteins. Particularl...

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