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TP53 BRCA1 CRISPR single-cell cancer

Kolacinska(Agnieszka),Fendler(Wojciech),Sz... Mol Biol Rep 2012-11-23

...PIK3CA, TGFB3, TOP2A, and YWHAZ receptor status of breast cancer core biopsies sampled before neoadjuvant chemotherapy (...

Cejas(P),López-Gómez(M),Aguayo(C),Madero(R... Curr Cancer Drug Targets 2012-07-16

...PIK3CA mutational status and for EGFR, PTEN and pAKT expression, and the number of concordant pairs was 70 (100%), 66 (9...

Rekhtman(Natasha),Paik(Paul K),Arcila(Mari... Clin Cancer Res 2012-06-13

...PIK3CA, NRAS, AKT1, ERBB2/HER2, and MAP2K1/MEK1. In addition, all tissue samples from rare patients with the diagnosis o...

Yang(Xi),Dong(Ying),Zhang(Xiao-ming),Liang... Zhonghua Bing Li Xue Za Zhi 2012-11-08

...PIK3CA mutation was 41.2% (14/34) with a hot mutation spot at T544 in exon 9. PIK3CA mutations more commonly occurred in...

Liao(Xiaoyun),Morikawa(Teppei),Lochhead(Pa... Clin Cancer Res 2012-08-31

...PIK3CA exon 9 and 20 mutations might confer aggressive tumor behavior.,We sequenced PIK3CA by pyrosequencing in 1,170 re...

Colombino(M),Sperlongano(P),Izzo(F),Tatang... Cell Death Dis 2012-07-24

Poor data have been previously reported about the mutation rates in K-RAS, BRAF, and PIK3CA genes among patients with he...

Hernandez(Lucia),Wilkerson(Paul M),Lambros... J Pathol 2012-05-22

...PIK3CA mutations restricted to the DCIS component in two cases, and in a third case the frequency of the PIK3CA mutant a...

Bhattacharya(Bhaskar),Akram(Mohamed),Balas... Cancer Biol Ther 2012-09-19

...PIK3CA were examined by siRNA, and mTOR by rapamycin exposure. Protein expression and apoptosis pre- and post-treatment ...

Pu(Xia),Hildebrandt(Michelle A T),Lu(Charl... Lung Cancer 2011-03-28

...PIK3CA, PTEN, AKT1, AKT2, and FRAP1) of this pathway and identified SNPs associated with development of toxicity and dis...

Shima(Kaori),Nosho(Katsuhiko),Baba(Yoshifu... Int J Cancer 2011-02-01

...PIK3CA mutations; and expression of TP53 (p53), CTNNB1 (β-catenin), CDKN1A (p21), CDKN1B (p27), CCND1 (cyclin D1), FASN ...

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