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Selective PI3K inhibition by BKM120 and BEZ235 alone or in combination with c...

Mueller(Annett),Bachmann(Erika),Linnig(Mon... Cancer Chemother Pharmacol 2012-08-03

...PIK3CA gene mutation status were used. Firstly, viability, apoptosis and caspase assays were performed during incubation...

Correlation of DLC1 gene methylation with oncogenic PIK3CA mutations in extra...

Kang(Zhihua),Xu(Feng),Zhang(Qiao-An),Lin(J... Mod Pathol 2012-12-20

...PIK3CA mutations significantly correlated with DLC1 hypermethylation. Thus, aberrant DLC1 methylation and PIK3CA mutatio...

Utility of cell-free tumour DNA for post-surgical follow-up of colorectal can...

Levy(Miroslav),Benesova(Lucie),Lipska(Ludm... Anticancer Res 2012-07-30

...PIK3CA and BRAF. All patients were tested positive for tumour cfDNA prior to surgery. cfDNA was then evaluated within a ...

A molecularly annotated platform of patient-derived xenografts ("xenopatients...

Bertotti(Andrea),Migliardi(Giorgia),Galimi... Cancer Discov 2012-11-21

...PIK3CA wild-type cases. Importantly, HER2 amplification was also enriched in clinically nonresponsive KRAS wild-type pat...

KRAS, BRAF and PIK3CA mutations and the loss of PTEN expression in Chinese pa...

Mao(Chen),Zhou(Junhua),Yang(Zuyao),Huang(Y... PLoS One 2012-09-26

To investigate the frequency and relationship of the KRAS, BRAF and PIK3CA mutations and the loss of PTEN expression in ...

Characteristics and prevalence of KRAS, BRAF, and PIK3CA mutations in colorec...

Hsieh(Li-Ling),Er(Tze-Kiong),Chen(Chih-Chi... Clin Chim Acta 2012-11-28

...PIK3CA mutations in the Taiwanese population with colorectal cancer. This study was undertaken to identify BRAF and PIK3...

PIK3CA mutations in endometrial carcinomas in Chinese women: phosphatidylinos...

Dong(Ying),Yang(Xi),Wong(Oscar),Zhang(Xiao... Hum Pathol 2012-10-25

...PIK3CA mutations and phosphatidylinositol 3'-kinase pathway alterations in endometrial cancers in Chinese women. The PIK...

Immunomarkers in gynecologic cytology: the search for the ideal 'biomolecular...

Pinto(Alvaro P),Degen(Martin),Villa(Luisa ... Acta Cytol 2012-05-15

...PIK3CA, as well the combination of biomarkers such as p16(INK4A) and MIB-1 in the same assay. Although none of them has ...

Riedel's thyroiditis - a case report with genes' expression studies.

Wojciechowska-Durczyńska(Katarzyna),Durczy... Thyroid Res 2012-10-02

...PIK3CA and CDH3 genes and Riedel's thyroiditis is not well-defined. However, the increased expression of PIK3CA and CDH3...

Comparative genomics of esophageal adenocarcinoma and squamous cell carcinoma...

Bandla(Santhoshi),Pennathur(Arjun),Luketic... Ann Thorac Surg 2012-06-15

...PIK3CA, FGFR1). Other regions contain putative oncogenes that may be targeted in the future.,Using single nucleotide pol...

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