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TP53 BRCA1 CRISPR single-cell cancer

Xu(Jianping),He(Jiaying),Yang(Huiyi),Luo(X... Cancer Biomark 2012-07-25

The prevalence of EGFR, KRAS, BRAF and PIK3CA somatic mutations in 861 randomly selected Chinese patients with non-small...

Yamauchi(Mai),Morikawa(Teppei),Kuchiba(Aya... Gut 2012-07-13

...PIK3CA mutations) were examined along bowel subsites (rectum, rectosigmoid junction, sigmoid, descending colon, splenic ...

Higgins(Michaela J),Jelovac(Danijela),Barn... Clin Cancer Res 2012-12-20

...PIK3CA mutations by BEAMing. We then prospectively screened the ctDNA of 60 patients with metastatic breast cancer for P...

Meric-Bernstam(Funda),Akcakanat(Argun),Che... Clin Cancer Res 2012-06-28

...PIK3CA and/or PTEN mutations were more likely to be RS (P = 0.0123). Akt phosphorylation (S473 and T308) was significant...

Byron(Sara A),Gartside(Michael),Powell(Mat... PLoS One 2012-08-27

Mutations in multiple oncogenes including KRAS, CTNNB1, PIK3CA and FGFR2 have been identified in endometrial cancer. The...

Ruppert(Anne-Marie),Antoine(Martine),Beau-... Bull Cancer 2012-07-11

...PIK3CA have potential clinical relevance with possible approval of novel tailored treatment and will be discussed in thi...

Ulivi(Paola),Capelli(Laura),Valgiusti(Mart... J Transl Med 2012-10-31

...PIK3CA was evaluated by pyrosequencing and PTEN expression by immunohistochemistry.,BRAF and PIK3CA mutations were indep...

Carden(Craig P),Stewart(Adam),Thavasu(Para... Mol Cancer Ther 2012-10-31

...PIK3CA and AKT, were sequenced by PCR-amplified mass spectroscopy detection methods. In addition, PIK3CA and AKT2 amplif...

Armaghany(Tannaz),Wilson(Jon D),Chu(Quyen)... Gastrointest Cancer Res 2012-10-02

...PIK3CA genes have also been recently described. Herein we briefly discuss the basic concepts of genetic integrity and th...

Kawamoto(Y),Tsuchihara(K),Yoshino(T),Ogasa... Br J Cancer 2012-11-21

...PIK3CA mutations were evaluated.,The numbers of primary lesions with wild-type and mutant KRAS codons 12 and 13 were 8 a...

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