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High frequency of mutations in the PIK3CA gene helical and kinase coding regi...

Derakhshandeh-Peykar(Pupak),Alivi(Jalil),H... J Neurogenet 2012-08-23

...PIK3CA gene, the helical and kinase domains (encoded by exons 9 and 20, respectively) in GBM and AA, the authors examine...

A PIK3CA pyrosequencing-based assay that excludes pseudogene interference.

Baker(Christine L),Vaughn(Cecily P),Samowi... J Mol Diagn 2012-04-03

...PIK3CA mutations. In KRAS-mutated samples, 20% had an additional mutation in PIK3CA. The mutation rate in KRAS wild-type...

Different subtypes of intraductal papillary mucinous neoplasm in the pancreas...

Mohri(Dai),Asaoka(Yoshinari),Ijichi(Hideak... J Gastroenterol 2012-06-19

...PIK3CA genes and expression of CDKN2A, TP53, SMAD4, phospho-ERK, and phospho-SMAD1/5/8 proteins were examined.,There wer...

Tumor TP53 expression status, body mass index and prognosis in colorectal can...

Morikawa(Teppei),Kuchiba(Aya),Liao(Xiaoyun... Int J Cancer 2012-09-20

...PIK3CA. TP53 positivity was not significantly associated with cancer-specific survival in univariate analysis with HR of...

PIK3CA exon 20 mutations as a potential biomarker for resistance to anti-EGFR...

Mao(C),Yang(Z Y),Hu(X F),Chen(Q),Tang(J L) Ann Oncol 2012-09-20

...PIK3CA exon of the mutations, in which PIK3CA exon 20 mutations were statistically significantly associated with shorter...

Evaluation of variation in the phosphoinositide-3-kinase catalytic subunit al...

Stevens(K N),Garcia-Closas(M),Fredericksen... Br J Cancer 2012-01-19

Somatic mutations in phosphoinositide-3-kinase catalytic subunit alpha (PIK3CA) are frequent in breast tumours and have ...

Comparative genomic hybridization for the analysis of unbalanced chromosomal ...

Curtis(L J) Methods Mol Med 2012-10-02

...PIK3CA (7).

Pancreatic endocrine tumours: mutational and immunohistochemical survey of pr...

Corbo(V),Beghelli(S),Bersani(S),Antonello(... Ann Oncol 2012-04-11

...PIK3CA, respectively.,Only rare PET cases, harbouring either HER2 amplification or KIT mutation, might benefit from targ...

Oncogenic events associated with endometrial and ovarian cancers are rare in ...

Vestergaard(Anna L),Thorup(Katrine),Knudse... Mol Hum Reprod 2012-04-02

...PIK3CA, TP53 and PTEN) were analyzed for mutations using denaturing gradient gel electrophoresis and direct sequencing. ...

Perifosine plus docetaxel in patients with platinum and taxane resistant or r...

Fu(Siqing),Hennessy(Bryan T),Ng(Chaan S),J... Gynecol Oncol 2012-10-31

...PIK3CA mutation had stable disease (SD) for 4 months. Two other patients without apparent PI3K pathway aberrations achie...

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