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TP53 BRCA1 CRISPR single-cell cancer

Sjödahl(Gottfrid),Lauss(Martin),Lövgren(Kr... Clin Cancer Res 2012-12-20

...PIK3CA, and TP53 mutation frequency. The molecular subtypes cut across pathologic classification, and class-defining gen...

Armaghany(Tannaz),Wilson(Jon D),Chu(Quyen)... Gastrointest Cancer Res 2012-10-02

...PIK3CA genes have also been recently described. Herein we briefly discuss the basic concepts of genetic integrity and th...

Mao(Chen),Zhou(Junhua),Yang(Zuyao),Huang(Y... PLoS One 2012-09-26

To investigate the frequency and relationship of the KRAS, BRAF and PIK3CA mutations and the loss of PTEN expression in ...

Bertotti(Andrea),Migliardi(Giorgia),Galimi... Cancer Discov 2012-11-21

...PIK3CA wild-type cases. Importantly, HER2 amplification was also enriched in clinically nonresponsive KRAS wild-type pat...

Hsieh(Li-Ling),Er(Tze-Kiong),Chen(Chih-Chi... Clin Chim Acta 2012-11-28

...PIK3CA mutations in the Taiwanese population with colorectal cancer. This study was undertaken to identify BRAF and PIK3...

Juanpere(Nuria),Agell(Laia),Lorenzo(Marta)... Hum Pathol 2012-11-29

...PIK3CA (PIK3CA(mut)) genotypes were associated with low-grade bladder tumors and mutated PIK3CA (PIK3CA(mut))-mutated KR...

Pinto(Alvaro P),Degen(Martin),Villa(Luisa ... Acta Cytol 2012-05-15

...PIK3CA, as well the combination of biomarkers such as p16(INK4A) and MIB-1 in the same assay. Although none of them has ...

Li(Shao-Ying),Wang(Wei),Li(Jian-Mei),Wang(... Zhonghua Zhong Liu Za Zhi 2012-11-26

...PIK3CA) occur in a variety of cancer types. The purpose of this study was to determine the relationship between PIK3CA m...

Kim(Ji Eun),Stones(Clare),Joseph(Wayne R),... BMC Cancer 2012-07-25

...PIK3CA, PTEN, NRAS and BRAF mutational status.,Western blotting was used to compare the phosphorylation status of compon...

Zang(Zhi Jiang),Cutcutache(Ioana),Poon(Son... Nat Genet 2012-07-02

...PIK3CA (3/15) and ARID1A (3/15). Cell adhesion was the most enriched biological pathway among the frequently mutated gen...

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