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TP53 BRCA1 CRISPR single-cell cancer

Nardi(Valentina),Song(Youngchul),Santamari... Clin Cancer Res 2012-06-26

...PIK3CA gene (6 of 60). Sanger sequencing of the primary MCC tumors detected one additional PIK3CA mutation (R19K) that h...

Papa(Anselmo),Rossi(Luigi),Lo Russo(Giusep... Recent Pat Anticancer Drug ... 2012-08-06

...PIK3CA/PTEN, have independently been found to give rise to resistance. The first-line trials with cetuximab chemotherapy...

Paulson(Lorien),Shindo(Maisie),Schuff(Kath... Arch Otolaryngol Head Neck ... 2012-04-03

...PIK3CA, and their variants.,Academic medical center.,Three hundred eighty-nine patients with PTC.,Molecular mutations in...

Garrido-Laguna(Ignacio),Hong(David S),Jank... PLoS One 2012-09-17

...PIK3CA mutations were marginally correlated with mucinous tumors (p = 0.05). In the univariate analysis, KRAS and PIK3CA...

Corver(Willem E),Ruano(Dina),Weijers(Karin... PLoS One 2012-10-11

...PIK3CA/AKT and MAPK pathways.,All FTC-OVs showed a very distinct pattern of genomic alterations. Ten out of 10 FTC-OV ca...

Kalender Atak(Zeynep),De Keersmaecker(Kim)... PLoS One 2012-10-11

...PIK3CA, and PTEN. Interestingly, we also found mutations in several cancer genes that had not been linked to T-ALL befor...

Kiyose(Shin-ichiro),Nagura(Kiyoko),Tao(Hon... Pathol Int 2012-11-19

...PIK3CA, MET, PTK7, ACK1, STK15, SRC, and HCK showed detectable amplifications in paraffin-embedded tissue in 2.83% to 13...

Gulhati(Pat),Zaytseva(Yekaterina Y),Valent... Carcinogenesis 2012-10-31

...PIK3CA mutations are partially sensitive to either rapamycin or sorafenib monotherapy, but highly sensitive to combinati...

Xiong(Donghai),Li(Guangming),Li(Kezhen),Xu... Carcinogenesis 2012-10-31

...PIK3CA, and ROS1), this study revealed "novel" genes not previously implicated in NSCLC. Especially, matrix-remodeling a...

Kurek(Kyle C),Luks(Valerie L),Ayturk(Ugur ... Am J Hum Genet 2012-08-23

...PIK3CA in all six individuals, and mutant allele frequencies ranged from 3% to 30% in affected tissue from multiple embr...

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