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TP53 BRCA1 CRISPR single-cell cancer

Gadducci(Angiolo),Guerrieri(Maria Elena),G... Gynecol Endocrinol 2012-12-10

...PIK3CA and ARID1A. Type II tumours, accounting for 75% of the cases, have a very aggressive biological behaviour, are us...

Koumaki(Dimitra),Kostakis(George),Koumaki(... Oncol Rep 2012-07-23

...PIK3CA gene mutations in the Greek population, we hypothesized that BRAF or HRAS may be activated as upstrea...

Davies(Barry R),Greenwood(Hannah),Dudley(P... Mol Cancer Ther 2012-10-16

...PIK3CA and/or PTEN mutations and sensitivity to AZD5363 and between RAS mutations and resistance. Oral dosing of AZD5363...

Jiao(Xiang),Wood(Laura D),Lindman(Monica),... Genes Chromosomes Cancer 2012-07-16

...PIK3CA pathways in breast cancer development, and point to novel processes that likely are involved.

Ludovini(V),Bianconi(F),Pistola(L),Pistola... Cancer Chemother Pharmacol 2012-06-18

We present a comprehensive analysis of KRAS, PIK3CA, MET, and non-sensitizing EGFR mutations in advanced non-small cell ...

Chakrapani(Andrea),Warrick(Andrea),Nelson(... Am J Dermatopathol 2012-11-29

...PIK3CA. A BRAF V600E mutation was identified in 3 cases, all of which occurred in proximal locations (upper shin, thigh,...

Sood(Arjun),McClain(Danielle),Maitra(Radha... Clin Colorectal Cancer 2012-08-30

...PIK3CA, PIK3R1, AKT1, and PTEN genes. PTEN promoter methylation status was analyzed by methylation-specific polymerase c...

Shi(Jing),Yao(Demao),Liu(Wei),Wang(Na),Lv(... BMC Cancer 2012-06-25

...PIK3CA mutations and amplification were found in 8/113 (7.1%) and 88/131 (67%) gastric cancer patients, respectively. PI...

Kinross(Kathryn M),Montgomery(Karen G),Kle... J Clin Invest 2012-04-20

...PIK3CA in the initiation or progression of tumorigenesis, we generated mice in which a PIK3CA mutation commonly detected...

Martins(Filipe C),De(Subhajyoti),Almendro(... Cancer Discov 2012-09-28

...PIK3CA is rarely detected. We also observed intratumor heterogeneity for the loss of wild-type BRCA1 and increased cell ...

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