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TP53 BRCA1 CRISPR single-cell cancer

Loyo(Myriam),Li(Ryan J),Bettegowda(Chetan)... Head Neck 2013-08-15

...PIK3CA, and CDKN2A. Emphasis is placed on the involved cellular pathways, clinical correlations, and potential therapeut...

Lang(Qingbo),Ling(Changquan) Biochem Biophys Res Commun 2013-01-31

...PIK3CA) is a novel target of miR-124 in HepG2 cells. Overexpression of miR-124 resulted in decreased expression of PIK3C...

Isoyama(Sho),Yoshimi(Hisashi),Dan(Shingo),... Biol Pharm Bull 2013-01-24

...PIK3CA) or dysfunction of phosphatase and tensin homolog deleted on chromosome 10 (PTEN). Therefore PI3K is thought to b...

Seo(Jeong-Sun),Ju(Young Seok),Lee(Won-Chul... Genome Res 2013-04-11

...PIK3CA, MET, and CTNNB1. Candidates for novel driver mutations were also identified in genes newly implicated in lung ad...

Abe(Azusa),Minaguchi(Takeo),Ochi(Hiroyuki)... Hum Pathol 2013-03-29

...PIK3CA overexpression in the disease. We performed immunohistochemical analyses of PIK3CA, PTEN, p-Akt, p27 and p53 expr...

Brandi(Giovanni),Tavolari(Simona),De Rosa(... PLoS One 2013-02-22

...PIK3CA or BRAF/PIK3CA mutation), while cetuximab affected these parameters only in CRC cells with KRAS, BRAF and PIK3CA ...

Capodanno(Alessandra),Boldrini(Laura),Alì(... Oncol Rep 2013-03-14

...PIK3CA gene status in BP-NETs has yet to be explored. This study aimed to investigate the PIK3CA gene status...

Arcila(Maria E),Chaft(Jamie E),Nafa(Khedou... Clin Cancer Res 2013-03-22

...PIK3CA, MEK1, and AKT was conducted by mass spectrometry. ALK rearrangements and HER2 amplification were assessed by FIS...

Mallucci(Livio),Shi(Dong-yun),Davies(Derek... Mol Cancer Ther 2013-02-07

...PIK3CA. Our study unveils an elective route to intrinsic and extrinsic apoptosis, which involves the cytoskeleton. Early...

Imamura(Yu),Morikawa(Teppei),Liao(Xiaoyun)... Clin Cancer Res 2013-04-09

...PIK3CA mutations, microsatellite instability, CpG island methylator phenotype, and LINE-1 methylation.,Compared with pat...

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