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TP53 BRCA1 CRISPR single-cell cancer

Rahman(Munmun),Nakayama(Kentaro),Ishibashi... Int J Mol Sci 2013-03-19

...PIK3CA mutation. The present case suggests a role for targeted therapies in the treatment of OCCC and a need for the ide...

Ganly(Ian),Ricarte Filho(Julio),Eng(Stepha... J Clin Endocrinol Metab 2013-07-05

...PIK3CA, MAP2K1, and AKT1. In addition, common oncogenic fusions of RET and NTRK1 as well as PAX8/PPARγ and AKAP9-BRAF we...

Massacesi(Cristian),di Tomaso(Emmanuelle),... Ann N Y Acad Sci 2013-10-25

...PIK3CA gene encoding the p110α catalytic subunit of PI3K, and inactivation of PTEN through mutation, deletion, or epigen...

Wik(Elisabeth),Birkeland(Even),Trovik(Jone... Clin Cancer Res 2013-11-12

...PIK3CA copy number (FISH) and a PI3K activation score (all P < 0.05).,High pStathmin(S38) is a novel biomarker of increa...

Tan(D S P),Miller(R E),Kaye(S B) Br J Cancer 2013-07-15

...PIK3CA and inactivation of PTEN, and increased activity of pathways involved in angiogenesis. Targeting HER2, apoptotic ...

Mezzapelle(R),Miglio(U),Rena(O),Paganotti(... Br J Cancer 2013-07-15

...PIK3CA and BRAF gene mutations by direct sequencing.,Gene mutations were identified in nine cases (12%): five KRAS, thre...

De(Pradip),Hasmann(Max),Leyland-Jones(Bria... Cancer Treat Rev 2013-10-28

...PIK3CA), loss of phosphatase and tensin homolog (PTEN), activation of other downstream signal transducers, prevention of...

Murtaza(Muhammed),Dawson(Sarah-Jane),Tsui(... Nature 2013-06-25

...PIK3CA (phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha) following treatment with paclitaxel; a ...

Thommen(François),Hewer(Ekkehard),Schäfer(... Clin Neuropathol 2013-11-15

...PIK3CA gene involving an A→G transition at Nucleotide 3140. On the other hand, neither codeletion of chromosomes 1p/19q ...

Guedes(Joana G),Veiga(Isabel),Rocha(Patríc... BMC Cancer 2013-09-16

...PIK3CA (exons 9 and 20) was performed by high resolution melting (HRM) and positive cases were then sequenced.,One mutat...

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