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Landscape of somatic single-nucleotide and copy-number mutations in uterine s...

Zhao(Siming),Choi(Murim),Overton(John D),B... Proc Natl Acad Sci U S A 2013-04-26

...PIK3CA, ERBB2 (an upstream activator of PIK3CA), and CCNE1 (a target of FBXW7-mediated ubiquitination). These findings i...

Stool DNA testing for the detection of colorectal neoplasia in patients with ...

Kisiel(J B),Yab(T C),Nazer Hussain(F T),Ta... Aliment Pharmacol Ther 2013-07-18

...PIK3CA genes were insufficiently informative, but several aberrantly methylated genes were highly discriminant. In the s...

Oncogenic driver mutations in patients with non-small-cell lung cancer at var...

Zhou(J X),Yang(H),Deng(Q),Gu(X),He(P),Lin(... Ann Oncol 2013-12-19

...PIK3CA mutations and 3 had MEK1 mutations. EML4-ALK, PIK3CA, and MEK1 mutations were mutually exclusive. EML4-ALK fusion...

Optimizing treatment of metastatic colorectal cancer patients with anti-EGFR ...

Troiani(Teresa),Zappavigna(Silvia),Martine... Expert Opin Biol Ther 2013-06-19

...PIK3CA, loss of expression of PTEN and, now, activation of HER2 signaling through HER2 gene amplification and/or increas...

Mutation scanning using MUT-MAP, a high-throughput, microfluidic chip-based, ...

Patel(Rajesh),Tsan(Alison),Tam(Rachel),Des... PLoS One 2013-06-17

...PIK3CA, NRAS, BRAF, and AKT1 oncogenes. The DNA was preamplified using custom-designed primer sets before the TaqMan/AS-...

Identification of uncommon PIK3CA mutations in lung cancer by using pyroseque...

Schildgen(Verena),Lüsebrink(Jessica),Appel... Diagn Mol Pathol 2013-07-26

...PIK3CA gene, using a pyrosequencing assay.,Pyrosequencing revealed 2 mutations (4.9%) in the PIK3CA gene, one in exon 9 ...

Biomarkers of benefit from cetuximab-based therapy in metastatic colorectal c...

Pentheroudakis(George),Kotoula(Vassiliki),... BMC Cancer 2013-08-28

...PIK3CA.,Only PIK3CA mutations occasionally coexisted with other gene mutations. In univariate analysis, prognostic signi...

Feasibility of Induction Docetaxel, Cisplatin, 5-Fluorouracil, Cetuximab (TPF...

Charalambakis(Nikolaos),Kouloulias(Vassili... Front Oncol 2013-02-04

...PIK3CA genes and high risk HPV DNA detection using PCR.,Mean time of follow-up was 16 months. Six patients were TNM Stag...

Novel method for PIK3CA mutation analysis: locked nucleic acid--PCR sequencin...

Ang(Daphne),O'Gara(Rebecca),Schilling(Amy)... J Mol Diagn 2013-12-04

...PIK3CA. We tested 60 FFPE breast DNA samples with known PIK3CA mutation status (48 cases had one or more PIK3CA mutation...

Gene mutations in squamous cell NSCLC: insignificance of EGFR, KRAS and PIK3C...

Fiala(Ondrej),Pesek(Milos),Finek(Jindrich)... Anticancer Res 2013-06-11

...PIK3CA mutations in 3.8% of patients. No correlation of EGFR or PIK3CA mutation status with progression-free survival (P...

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