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TP53 BRCA1 CRISPR single-cell cancer

Bozzao(Cristina),Varvara(Dora),Piglionica(... Int J Biol Markers 2013-09-05

...PIK3CA exon 20. The prevalence of BRAF and PIK3CA mutations was significantly higher in patients older than 65 years (p=...

Bando(Hideaki),Yoshino(Takayuki) Gan To Kagaku Ryoho 2013-01-07

...PIK3CA may also predict resistance to anti-EGFR antibodies in colorectal cancer patients. On the other hand, the continu...

Young(Natalie R),Liu(Jing),Pierce(Carolyn)... Mol Oncol 2013-12-23

...PIK3CA mutations were found in two resistant cell lines where pAKT was not inhibited by gefitinib. In resistant cell lin...

Zuiverloon(Tahlita C M),Beukers(Willemien)... J Urol 2013-06-17

...PIK3CA and RAS mutation analysis, and microsatellite and methylation analysis on tissue and urine DNA samples.,We obtain...

Biscuola(Michele),Van de Vijver(Koen),Cast... Hum Pathol 2013-06-20

...PIK3CA (PI3K catalytic alpha polypeptide) and 1 in AKT) and/or RAS/BRAF (serine/threonine-protein kinase B-raf) pathway ...

Kim(Jeong Goo),Takeshima(Hideyuki),Niwa(To... Cancer Lett 2013-05-09

...PIK3CA, SMARCB1, and TP53). Integration of information on the genetic and epigenetic alterations revealed that the GCs w...

Rekhtman(Natasha),Tafe(Laura J),Chaft(Jami... Mod Pathol 2013-11-07

...PIK3CA and AKT1 mutations). The immunomarkers classified large-cell carcinomas as variants of adenocarcinoma (n=62; 60%)...

Ushijima(Toshikazu),Yoshida(Satoshi) Nihon Rinsho 2013-02-19

...PIK3CA, CTNNB1, KRAS, and ERBB2, are activated by point mutations and gene amplification. Tumor-suppressor genes, such a...

Xing(Jeffrey C),Tufano(Ralph P),Murugan(Av... PLoS One 2013-05-14

...PIK3CA amplification (P = 0.01). Conversely, 1.5% (1/68) cases with PIK3CA amplification vs. 10.4% (33/318) cases withou...

Nardi(Valentina),Sadow(Peter M),Juric(Deja... Clin Cancer Res 2013-07-03

...PIK3CA, and 8 (30%) cases of HER2 gene amplification. To our knowledge, this is the first time that BRAF and PIK3CA muta...

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