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TP53 BRCA1 CRISPR single-cell cancer

,Kandoth(Cyriac),Schultz(Nikolaus),Chernia... Nature 2013-06-25

...PIK3CA, ARID1A and KRAS and novel mutations in the SWI/SNF chromatin remodelling complex gene ARID5B. A subset of endome...

Hao(Yujun),Wang(Chao),Cao(Bo),Hirsch(Brett... Cancer Cell 2013-07-22

PIK3CA, which encodes the p110α catalytic subunit of phosphatidylinositol 3-kinase α, is frequently mutated in human can...

Huang(Yu),Chen(Yu),Mei(Qin),Chen(Yuan),Yu(... Oncol Rep 2013-10-29

...PIK3CA wild‑type), NCI-H460 (PIK3CA mutant) and NCI-H661 (PIK3CA wild-type). All cell lines demonstrate a poor response ...

Dulak(Austin M),Stojanov(Petar),Peng(Shouy... Nat Genet 2013-06-18

...PIK3CA) have previously been implicated in EAC. The new significantly mutated genes include chromatin-modifying factors ...

Tinker(A V),Ellard(S),Welch(S),Moens(F),Al... Gynecol Oncol 2013-09-13

...PIK3CA by IHC, copy number analyses and PTEN promoter methylation status did not reveal subsets associated with disease ...

Zhang(Lina),Shi(Lei),Zhao(Xiaoting),Wang(Y... Onco Targets Ther 2013-05-16

...PIK3CA mutations in lung adenocarcinoma.,Five common PIK3CA mutations (E542K, E545K, and E545D mutation in exon 9, H1047...

Hohensee(Ina),Lamszus(Katrin),Riethdorf(Sa... Am J Pathol 2013-10-24

...PIK3CA) in 110 ductal carcinoma in situ, primary tumor, and metastatic BC samples. Alterations in EGFR, HER2, and PTEN, ...

Isella(Claudio),Mellano(Alfredo),Galimi(Fr... Ann Surg 2013-08-01

...PIK3CA were assessed on the same specimens with Sanger sequencing.,Receiver operating characteristic (ROC) analysis reve...

Kitano(Shiro),Myers(Jamie),Nakamura(Junko)... PLoS One 2013-12-24

KRAS, BRAF and PIK3CA mutations are frequently observed in colorectal cancer (CRC). In particular, KRAS mutations are st...

Eklöf(V),Wikberg(M L),Edin(S),Dahlin(A M),... Br J Cancer 2013-07-26

Mutations in KRAS, BRAF, PIK3CA and PTEN expression have been in focus to predict the effect of epidermal growth factor ...

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