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Chen(Z),Xiao(X),Zhao(Y),Li(Y),Wang(C),Zhao... Curr Pharm Des 2026-06-08

...PIK3CA. Molecular docking further validated potential binding of these compounds to inflammatory targets IL-6 and IL-1B,...

Rugo(HS),Curigliano(G),Cescon(DW),Penault-... Breast 2026-08-00

...PIK3CA), and visceral disease, are currently used to guide treatment decisions. However, international guidelines have v...

Di Lauro(V),Rizzo(A),Sacco(PC),Palma(V),Ci... Clin Breast Cancer 2026-07-00

...PIK3CA mutations are found in around 40% of cases and are associated with a poor prognosis. In BCs with alterations in t...

Wang(Q),Sun(J),Zhu(X),Yu(T),Xiao(X) Stem Cell Res Ther 2026-06-09

...PIK3CA disrupt endothelial homeostasis in both two-dimensional and three-dimensional contexts, leading to aberrant activ...

Wang(J),Wang(Y),Wang(Q),Zhao(T),Shen(H),Li... Int J Endocrinol None

...PIK3CA, was identified using a dual-luciferase assay. Exosomal miR-27a-5p differed significantly in PC and PA and was up...

Wang(F),Altelaar(M),Stecker(KE) J Proteome Res 2026-07-03

Activating PIK3CA mutations are among the most frequent oncogenic drivers in breast cancer, with E545K and H1047R mutant...

Sutrisno(E),Muslimawati(K),Sodik(JJ),Akbar... Toxicol Rep 2026-06-00

...PIK3CA (808), JAK2 (673), SRC (606), and ERBB2 (602). Docking showed that corynantheidine had the strongest affinity for...

Misar(PL),Otari(KV),Pande(VV),Ige(PP) Naunyn Schmiedebergs Arch P... 2026-08-00

...PIK3CA, PTK2, RPS6KB1, VEGFR, F2-thrombin, ULK3 kinase, and PI3K delta. Molecular docking demonstrated that cilostazol b...

Zhang(H),Yu(J),Ruan(R),Cui(Z),Tao(Y),Zhu(S... Discov Oncol 2026-05-28

...PIK3CA mutations. Pathway-level integrative analysis highlighted the Citrate cycle (TCA cycle) and Central carbon metabo...

Rakha(EA) Expert Rev Mol Diagn 2026-06-00

...PIK3CA, AKT, mTOR, and PTEN increasingly informs targeted treatment, particularly in advanced disease. Emerging approach...