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Prospective, high-throughput molecular profiling of human gliomas.

Chi(Andrew S),Batchelor(Tracy T),Dias-Sant... J Neurooncol 2013-04-23

...PIK3CA closely matched frequencies reported in recent studies. In addition, we identified events that are rare in glioma...

Insulin-like growth factor 2 messenger RNA binding protein 3 (IGF2BP3) is a m...

Lochhead(Paul),Imamura(Yu),Morikawa(Teppei... Eur J Cancer 2013-02-14

...PIK3CA mutations.,Among 671 colorectal cancers, 234 (35%) tumours were positive for IGF2BP3. In contrast, normal colorec...

Array CGH and PIK3CA/AKT1 mutations to drive patients to specific targeted ag...

Arnedos(M),Scott(V),Job(B),De La Cruz(J),C... Eur J Cancer 2013-03-07

Breast cancer includes high number of molecular entities targetable by specific agents. In this study, array CGH and PIK...

Gene network profiling before and after transplantation in alcoholic cirrhosi...

Muffak-Granero(K),Olmedo(C),Garcia-Alcalde... Transplant Proc 2013-01-03

...PIK3CA (phosphoinositide-3-kinase, catalytic, alpha polypeptide); IFNGR2 (interferon gamma receptor 2); JAK2 (Janus Kina...

PI3K expression and PIK3CA mutations are related to colorectal cancer metasta...

Zhu(Yu-Fen),Yu(Bao-Hua),Li(Da-Li),Ke(Hong-... World J Gastroenterol 2013-01-10

...PIK3CA mutations were investigated by gene sequencing analysis. A flow-cytometry-based apoptosis detection kit was used ...

A combined oncogenic pathway signature of BRAF, KRAS and PI3KCA mutation impr...

Tian(Sun),Simon(Iris),Moreno(Victor),Roepm... Gut 2013-05-16

...PIK3CA (11.5%). Activating mutation signatures for KRAS (75 genes), for BRAF (58 genes,) and for PIK3CA (49 genes) were ...

Mutation and genomic amplification of the PIK3CA proto-oncogene in pituitary ...

Murat(C B),Braga(P B S),Fortes(M A H Z),Br... Braz J Med Biol Res 2013-11-19

...PIK3CA mutation in one noninvasive corticotroph microadenoma. PIK3CA amplification was observed in 21.2% (7/33) of the c...

Combination of ATP-competitive mammalian target of rapamycin inhibitors with ...

Atreya(Chloe E),Ducker(Gregory S),Feldman(... Invest New Drugs 2013-04-04

...PIK3CA. Mutation of p53 predicts resistance to chemotherapy, but not PP242. Efficacy of PP242 was comparable to that of ...

Molecular characterization of de novo Philadelphia chromosome-positive acute ...

Konoplev(Sergej),Yin(C Cameron),Kornblau(S... Leuk Lymphoma 2013-05-15

...PIK3CA and RET. Two of nine (22%) patients with Ph+ AML had NPM1 mutations and were alive 36 and 71 months after diagnos...

KRAS mutation status and clinical outcome of preoperative chemoradiation with...

Kim(Sun Young),Shim(Eun Kyung),Yeo(Hyun Ya... Int J Radiat Oncol Biol Phy... 2013-02-19

...PIK3CA mutation status with direct sequencing and epidermal growth factor receptor (EGFR) and Phosphatase and tensin hom...

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