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TP53 BRCA1 CRISPR single-cell cancer

Isella(Claudio),Mellano(Alfredo),Galimi(Fr... Ann Surg 2013-08-01

...PIK3CA were assessed on the same specimens with Sanger sequencing.,Receiver operating characteristic (ROC) analysis reve...

Kitano(Shiro),Myers(Jamie),Nakamura(Junko)... PLoS One 2013-12-24

KRAS, BRAF and PIK3CA mutations are frequently observed in colorectal cancer (CRC). In particular, KRAS mutations are st...

Seymour(Matthew T),Brown(Sarah R),Middleto... Lancet Oncol 2013-09-09

...PIK3CA mutations, and predefined molecular subgroups were analysed for interaction with the effect of panitumumab. This ...

Ito(Yuriko),Yamada(Yasuhide),Asada(Kiyoshi... J Cancer Res Clin Oncol 2013-09-17

...PIK3CA exon 20. The objective of the study is to study the impact of EGFR L2 mutations on resistance to cetuximab in KRA...

Kim(Mi-Jung),Lee(Eun-Jung),Suh(Jung-Pil),C... Am J Clin Pathol 2013-12-31

...PIK3CA, and EGFR and immunohistochemical staining for Ki-67 were performed on 107 TSAs from 104 patients.,Nondysplastic ...

Huw(L-Y),O'Brien(C),Pandita(A),Mohan(S),Sp... Oncogenesis 2013-12-24

...PIK3CA mutant breast cancer cell line, KPL-4. We identified a heretofore-unreported mechanism of resistance, specificall...

Won(Hye Sung),Jung(Chan-Kwon),Chun(Sang Ho... Oral Oncol 2013-05-29

...PIK3CA, pAkt, mTOR, and PTEN was assessed by immunohistochemistry. In situ hybridization was used to detect the existenc...

Anforth(Rachael),Tembe(Varsha),Blumetti(Ta... Pigment Cell Melanoma Res 2013-01-03

...PIK3CA in both verrucal keratosis and cuSCC. This suggests that verrucal keratosis is an early clinical presentation of ...

Ren(Shengxiang),Kuang(Peng),Zheng(Limou),S... Cell Biochem Biophys 2013-03-04

...PIK3CA. 73 (70.2 %) tumors harbored EGFR mutations; among these, 28 were deletions in exon 19, 44 were L858R missense ch...

Dienstmann(Rodrigo),Serpico(Danila),Rodon(... Mol Cancer Ther 2013-02-07

...PIK3CA mutations (15 of 114, 13.2%), KRAS and PIK3CA mutations (9 of 114, 7.9%), low PTEN expression (97 of 183, 53.0%),...

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