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KRAS mutation testing in metastatic colorectal cancer.

Tan(Cong),Du(Xiang) World J Gastroenterol 2013-03-28

...PIK3CA and loss of PTEN proposed by many researchers and pathologists, should be promoted. In addition, we recommend tha...

Copy number variation in ACHE/EPHB4 (7q22) and in BCHE/MME (3q26) genes in sp...

Boberg(Dellyana R),Batistela(Meire S),Pech... Chem Biol Interact 2013-05-28

...PIK3CA (3q26), and thus being interesting targets for future studies in breast cancer research.

Association between genomic alterations and metastatic behavior of colorectal...

Sawada(Takeshi),Yamamoto(Eiichiro),Suzuki(... Genes Chromosomes Cancer 2013-05-23

...PIK3CA and DNA methylation of six marker genes in single glands isolated from 39 primary tumors. Array-based comparative...

Oncogenic PIK3CA mutations in lobular breast cancer progression.

Christgen(Matthias),Noskowicz(Monika),Schi... Genes Chromosomes Cancer 2013-07-23

...PIK3CA mutations in LRTs. Intriguingly, these findings imply that PIK3CA mutations are positively selected for during IL...

Going beyond EGFR.

Zimmermann(S),Peters(S) Ann Oncol 2013-04-26

...PIK3CA, with a special emphasis on aLK rearrangements, and outlines their potential therapeutic applications.

Everolimus in the treatment of hormone receptor-positive breast cancer.

Chavez-MacGregor(Mariana),Gonzalez-Angulo(... Expert Opin Investig Drugs 2013-04-18

...PIK3CA mutations and efficacy. The results of biomarker studies will hopefully provide information that will help us det...

Copy number amplification of the PIK3CA gene is associated with poor prognosi...

Suda(Toshihito),Hama(Takanori),Kondo(Shu),... BMC Cancer 2013-05-23

...PIK3CA. Copy number amplification was found in 37 cases (32.2%) for PIK3CA, 10 cases (8.7%) for K-RAS and 2 cases (1.7%)...

Molecular dissection of premalignant colorectal lesions reveals early onset o...

Yamamoto(Eiichiro),Suzuki(Hiromu),Yamano(H... Am J Pathol 2013-03-21

...PIK3CA pathway genes were examined in 84 colorectal lesions. Genome-wide methylation analysis of CpG islands and selecte...

Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades...

McCubrey(James A),Steelman(Linda S),Chappe... Oncotarget 2013-05-28

...PIK3CA, PIK3R1, PIK3R4, PIK3R5, IRS4, AKT, NFKB1, MTOR, PTEN, TSC1, and TSC2 may also be activated/inactivated by mutati...

Racial differences in oncogene mutations detected in early-stage low-grade en...

Cote(Michele L),Atikukke(Govindaraja),Rute... Int J Gynecol Cancer 2013-03-21

...PIK3CA and KRAS) in tumors from 19 women (12.7%). Most of the mutations were found in PIK3CA (16/20). Thirteen percent o...

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