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TP53 BRCA1 CRISPR single-cell cancer

Massacesi(Cristian),di Tomaso(Emmanuelle),... Ann N Y Acad Sci 2013-10-25

...PIK3CA gene encoding the p110α catalytic subunit of PI3K, and inactivation of PTEN through mutation, deletion, or epigen...

Thommen(François),Hewer(Ekkehard),Schäfer(... Clin Neuropathol 2013-11-15

...PIK3CA gene involving an A→G transition at Nucleotide 3140. On the other hand, neither codeletion of chromosomes 1p/19q ...

Guedes(Joana G),Veiga(Isabel),Rocha(Patríc... BMC Cancer 2013-09-16

...PIK3CA (exons 9 and 20) was performed by high resolution melting (HRM) and positive cases were then sequenced.,One mutat...

Yamaguchi(Hiroshi),Kuboki(Yuko),Hatori(Tak... J Pathol 2013-12-30

...PIK3CA, GNAS, KRAS, and BRAF were determined by Sanger sequencing. Expression of phosphorylated AKT was examined by immu...

Neumann(Jens),Wehweck(Laura),Maatz(Susanne... Virchows Arch 2013-11-18

...PIK3CA exons 9 and 20 were analyzed by pyrosequencing in 171 primary CRC samples as well as in 63 corresponding metastas...

Garrett(Joan T),Sutton(Cammie R),Kurupi(Ri... Cancer Res 2013-12-12

...PIK3CA mutant cell lines. The combination also inhibited P-AKT in HER2-overexpressing breast cancer cells and growth of ...

Schwarz(Julie K) Radiat Res 2013-11-06

...PIK3CA gene have been identified that are associated with poor prognosis after chemoradiation in cervical cancer. These ...

Donovan(Cory A),Pommier(Rodney F),Schillac... JAMA Surg 2013-12-04

Mutations in oncogenes AKT1, HRAS, and PIK3CA in breast cancers result in abnormal PI3K/Akt signaling and tumor prolifer...

Lochhead(Paul),Kuchiba(Aya),Imamura(Yu),Li... J Natl Cancer Inst 2013-09-30

...PIK3CA mutations. Compared with the majority subtype of microsatellite stable (MSS)/BRAF-wild-type, MSS/BRAF-mutant, MSI...

Hanker(Ariella B),Pfefferle(Adam D),Balko(... Proc Natl Acad Sci U S A 2013-11-22

...PIK3CA tumors were associated with claudin-low breast cancers. PIK3CA and HER2(+)/PIK3CA tumors expressed elevated trans...

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