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TP53 BRCA1 CRISPR single-cell cancer

Sangai(Takafumi),Akcakanat(Argun),Chen(Hui... Clin Cancer Res 2013-05-23

...PIK3CA mutations were significantly more sensitive to MK-2206; however, several lines with PTEN/PIK3CA mutations were MK...

Palomba(Grazia),Colombino(Maria),Contu(Ant... J Transl Med 2013-02-19

...PIK3CA was found mutated in 67 (17%) patients. A significant inverse distribution of PIK3CA mutation rates was observed ...

Zhou(Jingyi),Liao(Wenjuan),Yang(Jing),Ma(K... Autophagy 2013-05-08

...PIK3CA, leading to an increase in AKT1 activity, which resulted in the phosphorylation and nuclear export of FOXO1. To t...

Holdhoff(Matthias),Ye(Xiaobu),Blakeley(Jai... J Neurooncol 2013-04-11

...PIK3CA (0.8 %). The perceived utility of these studies was variable between participants. A small percentage of responde...

Capodanno(Alessandra),Boldrini(Laura),Alì(... Oncol Rep 2013-03-14

...PIK3CA gene status in BP-NETs has yet to be explored. This study aimed to investigate the PIK3CA gene status...

Abe(Azusa),Minaguchi(Takeo),Ochi(Hiroyuki)... Hum Pathol 2013-03-29

...PIK3CA overexpression in the disease. We performed immunohistochemical analyses of PIK3CA, PTEN, p-Akt, p27 and p53 expr...

Loyo(Myriam),Li(Ryan J),Bettegowda(Chetan)... Head Neck 2013-08-15

...PIK3CA, and CDKN2A. Emphasis is placed on the involved cellular pathways, clinical correlations, and potential therapeut...

Mallucci(Livio),Shi(Dong-yun),Davies(Derek... Mol Cancer Ther 2013-02-07

...PIK3CA. Our study unveils an elective route to intrinsic and extrinsic apoptosis, which involves the cytoskeleton. Early...

Arcila(Maria E),Chaft(Jamie E),Nafa(Khedou... Clin Cancer Res 2013-03-22

...PIK3CA, MEK1, and AKT was conducted by mass spectrometry. ALK rearrangements and HER2 amplification were assessed by FIS...

Imamura(Yu),Morikawa(Teppei),Liao(Xiaoyun)... Clin Cancer Res 2013-04-09

...PIK3CA mutations, microsatellite instability, CpG island methylator phenotype, and LINE-1 methylation.,Compared with pat...

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