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TP53 BRCA1 CRISPR single-cell cancer

Harlé(Alexandre),Lion(Maëva),Lozano(Nicola... Bull Cancer 2013-12-17

...PIK3CA mutation could explain some resistance to targeted therapies. PIK3CA mutations also appear to have a significant ...

Meyer(D S),Koren(S),Leroy(C),Brinkhaus(H),... Oncogenesis 2013-10-01

...PIK3CA(E545K) in the mouse mammary gland induces heterogenous mammary carcinomas but with a longer latency than PIK3CA(H...

Palimaru(Irina),Brügmann(Anja),Wium-Anders... Springerplus 2013-10-01

...PIK3CA expression (p = 0.59). Expression of PIK3CA and PTEN mRNA, and PIK3CA mutations in breast carcinomas were not ass...

Glaysher(S),Bolton(L M),Johnson(P),Atkey(N... Br J Cancer 2013-12-04

...PIK3CA mutation or amplification, or PTEN loss, although one tumour with a KRAS mutation showed resistance to EGFR inhib...

Vauthey(Jean-Nicolas),Zimmitti(Giuseppe),K... Ann Surg 2013-11-18

...PIK3CA in 13 (7%), and BRAF in 2 (1%) patients. At a median follow-up of 33 months, 3-year overall survival (OS) rates w...

Yu(Jinglin),Bai(Hua),Wang(Zhijie),Wei(Zhig... Chin J Cancer Res 2013-09-02

...PIK3CA mutation is low in Chinese patients with LSCC. The mutational status of PIK3CA is not mutually exclusive to EGFR ...

Yip(Wai Kien),Choo(Chee Wei),Leong(Vincent... APMIS 2013-11-14

Molecular alterations in KRAS, BRAF, PIK3CA, and PTEN have been implicated in designing targeted therapy for colorectal ...

Wright(Alexi A),Howitt(Brooke E),Myers(And... Cancer 2013-12-19

...PIK3CA) (31.3%); Kirsten rat sarcoma viral oncogene homolog (KRAS) (8.8%); and EGFR (3.8%). PIK3CA mutation rates did no...

Mouradov(Dmitri),Domingo(Enric),Gibbs(Pete... Am J Gastroenterol 2013-12-30

...PIK3CA, FBXW7, and TP53, and chromosome 18q loss-of-heterozygosity (LOH) in 822 patients from the VICTOR trial of stage ...

Ahmed(D),Eide(P W),Eilertsen(I A),Danielse... Oncogenesis 2013-09-17

...PIK3CA oncogenes were analyzed for mutations in known hotspots, while the entire coding sequences of the PTEN and TP53 t...

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