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TP53 BRCA1 CRISPR single-cell cancer

Miller(Todd W) Breast Cancer Res 2013-02-07

...PIK3CA in luminal mammary epithelial cells induces tumorigenesis, implying that PIK3CA mutation is an early event in bre...

Cizkova(Magdalena),Susini(Aurélie),Vacher(... Breast Cancer Res 2013-02-07

...PIK3CA mutation status is controversial.,We investigated the prognostic significance of PIK3CA mutation status in a seri...

Atreya(Chloe E),Ducker(Gregory S),Feldman(... Invest New Drugs 2013-04-04

...PIK3CA. Mutation of p53 predicts resistance to chemotherapy, but not PP242. Efficacy of PP242 was comparable to that of ...

Deelen(Joris),Uh(Hae-Won),Monajemi(Ramin),... Age (Dordr) 2013-06-18

...PIK3CA, SGK, SGK2, and YWHAG), while the association of the TM pathway seems to be mainly determined by one gene (POT1)....

Beckner(Marie E),Sampath(Raghuram),Flowers... World Neurosurg 2013-06-17

...PIK3CA) individually exhibited significantly higher CN ratios (P < 0.05) or a trend for them (P < 0.09), with correction...

Parmar(S),Schumann(C),Rüdiger(S),Boeck(S),... Pharmacogenomics J 2013-09-04

...PIK3CA gene was associated with skin rash (P=0.045) and overall survival (P=0.009). In conclusion, genetic variation wit...

Wu(Yi-he),Wang(Jue),Gong(Ding-xu),Gu(Hai-y... Lasers Med Sci 2013-03-08

...Pik3ca) were upregulated after LLLI, whereas those of protein tyrosine phosphatase non-receptor type 6 (Ptpn6) and serin...

Brandi(Giovanni),Tavolari(Simona),De Rosa(... PLoS One 2013-02-22

...PIK3CA or BRAF/PIK3CA mutation), while cetuximab affected these parameters only in CRC cells with KRAS, BRAF and PIK3CA ...

Seront(E),Rottey(S),Sautois(B),Kerger(J),D... Ann Oncol 2013-03-29

...PIK3CA mutations were correlated to disease control.,Two confirmed PR and eight SD were observed, resulting in a DCR of ...

Schepeler(T),Lamy(P),Hvidberg(V),Laurberg(... Oncogene 2013-10-01

...PIK3CA alleles, and also homozygous deletion of the CDKN2A tumor suppressor locus. The DDR signaling as evaluated by pho...

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