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Distinct effects of alcohol consumption and smoking on genetic alterations in...

Urashima(Mitsuyoshi),Hama(Takanori),Suda(T... PLoS One 2014-12-10

...PIK3CA (q=0.014), and CSMD1 (q=0.019). But, TP53 mutations were not affected. In contrast, smoking was associated with i...

Hsp70 inhibition potentiates radicicol-induced cell death in anaplastic thyro...

Kim(Si Hyoung),Kang(Jun Goo),Kim(Chul Sik)... Anticancer Res 2014-11-11

...PIK3CA plasmid-transfected cells, compared to cells treated with radicicol-alone, cell viability increased and cellular ...

Defined morphological criteria allow reliable diagnosis of colorectal serrate...

Rau(Tilman T),Agaimy(Abbas),Gehoff(Anastas... Virchows Arch 2014-07-29

...PIK3CA and the methylation status of MLH1. Gender, age and localisation were significantly associated with certain types...

Primary concomitant EGFR T790M mutation predicted worse prognosis in non-smal...

Li(Hang),Hu(Haichuan),Wang(Rui),Pan(Yunjia... Onco Targets Ther 2014-04-14

...PIK3CA (phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha), and EML4 (echinoderm microtubule assoc...

PIK3CA mutations are associated with lower rates of pathologic complete respo...

Loibl(Sibylle),von Minckwitz(Gunter),Schne... J Clin Oncol 2014-12-03

...PIK3CA mutation. Detection of a PIK3CA mutation was significantly associated with a lower pCR rate (19.4% with PIK3CA mu...

PIK3CA mutations define favorable prognostic biomarkers in operable breast ca...

Liu(Yi-Rong),Jiang(Yi-Zhou),Zuo(Wen-Jia),Y... Onco Targets Ther 2014-04-21

Mutations of the p110α catalytic subunit of phosphatidylinositol 3-kinase (PIK3CA) are among the most common genetic abe...

Genomic high-resolution profiling of single CKpos/CD45neg flow-sorting purifi...

Neves(Rui P L),Raba(Katharina),Schmidt(Oli... Clin Chem 2014-11-24

...PIK3CA) gene and exons 5, 7, and 8 of the tumor protein p53 (TP53) gene.,One common flow-sorting protocol was appropriat...

The target therapy of ovarian clear cell carcinoma.

Jin(Ying),Li(Yan),Pan(Lingya) Onco Targets Ther 2014-10-06

...PIK3CA and inactivation of PTEN, is involved in tumorigenesis of CCC. Targeting angiogenesis, the Met protooncogene path...

Phase II trial of temsirolimus in patients with metastatic breast cancer.

Fleming(Gini F),Ma(Cynthia X),Huo(Dezheng)... Breast Cancer Res Treat 2013-06-14

...PIK3CA mutations; no association was found between prolonged stable disease and PIK3CA mutation or any immunohistochemic...

Reciprocal effects of NNK and SLURP-1 on oncogene expression in target epithe...

Kalantari-Dehaghi(Mina),Bernard(Hans-Ulric... Life Sci 2013-01-24

...PIK3CA in BEP2D, ETS1, NRAS and SRC in Het-1A, and AKT1, KIT and RB1 in both cell types, which could be abolished in the...

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