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Yasuda(S),Oya(K),Ikuta(S),Takata(S),Nakata... BMC Oral Health 2026-06-29

...PIK3CA were observed in 60% of cases. Additionally, one patient had high TMB status. Given the challenges in diagnosis a...

Zhang(X),Wu(H),Zhao(W),Hu(Z),Wang(G),Li(Y)... Front Immunol None

...PIK3CA (22%) across tumor regions. Shared truncal mutations and copy-number alterations between ACC and SCCC regions sug...

Li(H),Liu(L),Yang(Q),Li(Y),Song(Y),Jiang(J... Mol Med Rep 2026-08-00

...PIK3CA and PIK3CB) were found to be enriched in the EGFR/PI3K/Akt signaling pathway. Molecular docking demonstrated stab...

Rathod(G),Parmar(P) Oncoscience None

...PIK3CA, PTEN, and AKT genes. Moreover, hyperactivation of the MAPK pathway can be caused by overexpression of RTKs, GPCR...

Le(KT),Tran(HD),Do(MD),Nguyen(TH),Nguyen(T... BMC Cancer 2026-06-11

...PIK3CA mutation (p = 0.036), and co-mutation of RAS/RAF and MMR genes (p = 0.011). However, when adjusted for disease st...

Tomoszková(S),Drozdková(D),Vaculová(J),Del... Int J Mol Sci 2026-05-22

...PIK3CA. MGMT promoter methylation, EGFR amplification, and TERT promoter mutation status were obtained from routine diag...

Wang(M),Zou(J),Zhang(Q),Bai(X),Wu(S),Hu(Y)... Int J Mol Sci 2026-06-05

...PIK3CA) identified as key hub proteins. Gene Ontology and KEGG pathway enrichment analyses indicated that AOK primarily ...

Tang(W),Zhou(J),Zhao(W),Lin(F),Xue(L),Guo(... Cancers (Basel) 2026-06-04

...PIK3CA-mutant), PIK3CA mutation (OS HR 6.19, p = 0.024) and bone metastasis (OS HR 5.84, p = 0.027) remained associated ...

Chen(M),Zhu(Y),Chen(J),Zhou(R),Li(G) Molecules 2026-06-04

...PIK3CA, and EGFR) to putatively exert anti-apoptotic and anti-inflammatory effects via the PI3K-Akt, TNF, and MAPK pathw...

Hofmann(E),Abu-Sirhan(S),Elsholtz(F),Piwon... NPJ Precis Oncol 2026-06-12

...PIK3CA. Personalized treatment recommendations were made for 13 patients, and 11 received matched therapies: dabrafenib ...