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Xiong(F),Wang(Q),Wang(SQ),Zheng(M),Zhong(H... Am J Med Genet A 2026-07-00

...PIK3CA gene constitutively activate the PI3K/AKT/mTOR pathway in patients with PIK3CA-related overgrowth spectrum (PROS)...

Sagar(K),Boscolo(E) Front Cardiovasc Med None

...PIK3CA genes, which disrupt endothelial cell morphogenesis and vessel maturation. VM lesions are typically diagnosed dur...

Solomon(H),Mukherjee(R),Yang(YC),Meredith(... bioRxiv 2026-02-14

...PIK3CA coexistent alterations result in elevated membrane phosphatidylinositol (3,4,5)-trisphosphate (PIP3) levels and m...

Yu(Q),Yang(Q),Yuan(S),Zhao(Y),Li(W),Qiao(J... Front Cell Dev Biol None

...PIK3CA. Subsequent MR analysis established TLR4 as being causally associated with an increased risk of NOA. In vitro exp...

Nozaki(F),Nakanishi(Y),Hirotani(Y),Kobayas... Breast Cancer 2026-05-00

...PIK3CA mutations (MDA-MB-453: ER-/HER2+/AR + and MFM223: ER-/HER2-/AR+) and one without PIK3CA mutations (HCC1428: ER+/H...

Yan(H),Zhu(S),Yu(J),Xu(X),Fu(D),Chen(Y),Da... Food Funct 2026-03-09

...PIK3CA, PIK3CB, and ESR1. These compounds synergistically reduced hepatic triglycerides (-59.3%) and cholesterol (-35.2%...

Ye(R),Dai(X),Yang(Z),Zhang(D),Hu(Z),Liao(Y... Breast Cancer (Dove Med Press) None

...PIK3CA (9/16, 56.2%), and MCL1 (10/16, 62.5% amplified). TP53 mutations (primarily frameshift and missense) showed consi...

Chauhan(C),Kaundal(RK) J Ethnopharmacol 2026-05-23

...PIK3CA, and HIF1A, with significant enrichment in the PI3K-Akt and HIF-1 signaling pathways. Experimental validation dem...

Jiang(S),Li(Y),Wu(S),Wan(J),Li(X) Front Immunol None

...PIK3CA, and ARID1A were the most frequently mutated genes, forming a conserved oncogenic core centered on PI3K/AKT signa...

Desai(C),Wang(P),Tjota(M),Lastra(RR) Int J Gynecol Pathol 2026-02-02

...PIK3CA, APC, and NF1. The aforementioned findings mirror those found in metaplastic carcinoma of the breast, and a diagn...