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Rice(J C),Ozcelik(H),Maxeiner(P),Andrulis(... Carcinogenesis 2000-10-02

...BRCA1 is an important mechanism involved in breast cancer pathogenesis. Mutation is often responsible for BRCA1 inactiva...

Niwa(Y),Oyama(T),Nakajima(T) Jpn J Cancer Res 2000-07-18

...BRCA1 in sporadic breast cancers, the relationship between DNA methylation of the BRCA1 promoter region and BRCA1 expres...

Matros(Evan),Wang(Zhigang C),Lodeiro(Gabri... Breast Cancer Res Treat 2005-07-25

...BRCA1 methylation and high levels of BRCA1 protein expression consistent with their high mitotic rate. Tumors with BRCA1...

Hu(Yiduo),Petit(Sarah A),Ficarro(Scott B),... Cancer Discov 2015-08-05

...BRCA1 and helps to maintain the stability of PARP1-BRCA1-RAP80 complexes. BRCA1 PARsylation is a key step in BRCA1 HRR c...

Sgagias(Magdalene K),Wagner(Kay-Uwe),Hamik... Cell Cycle 2007-08-07

...Brca1(++) and Brca1(-/-) murine mammary epithelial cells (MMECs). These cells were isolated from Brca1 conditional knock...

Liu(J),Prolla(G),Rostagno(A),Chiarle(R),Fe... Oncogene 2000-07-06

...BRCA1(17aa)). We fused cDNAs encoding the second exon of BRCA1 of the wild-type BRCA1 gene (wt-BRCA1) and a mutated BRCA...

Brodie(Kirsty M),Henderson(Beric R) J Biol Chem 2012-04-24

...BRCA1 causes centrosome amplification and abnormal mitotic spindle assembly in breast cancer cells. The BRCA1-BARD1 hete...

Fabbro(Megan),Henderson(Beric R) Cancer Lett 2008-06-24

...BRCA1, but repressed BRCA1-mediated transactivation by up to 75% in transfected cells normalized for nuclear BRCA1 level...

Bi(Fang-Fang),Li(Da),Cao(Chen),Li(Chun-Yan... J Ovarian Res 2013-12-16

...BRCA1-mutated ovarian cancer cells.,BRCA1 dysfunction (BRCA1 mutation or hypermethylated BRCA1 promoter) ovarian cancer ...

Song(Yong-Mei),Tong(Tong),Fu(Ming),Dong(Li... Ai Zheng 2005-03-22

...BRCA1. BRCA1 strongly activated the Gadd45 promoter. Antisense Gadd45 substantially abrogated BRCA1-activated cell cycle...