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TP53 BRCA1 CRISPR single-cell cancer

Tan(Daniel S W),Camilleri-Broët(Sophie),Ta... Int J Cancer 2014-08-13

...PIK3CA (8%), STK11 (6%) and MET (4%). Significant relationships were detected between EGFR mutation and 1p, 7p copy gain...

Pinto-Leite(Rosário),Carreira(Isabel),Melo... Tumour Biol 2014-06-24

...PIK3CA region which, in combination with the inactivation of TP53, bears more invasive and metastatic properties than 56...

Cui(Wenli),Cai(Ying),Wang(Weige),Liu(Zebin... J Transl Med 2014-09-05

...PIK3CA (P = 0.002) but also positively correlated with strong positive expression of pAKT (P = 0.026).,CNV of PIK3CA is ...

Ross(Jeffrey S),Wang(Kai),Rand(Janna V),Sh... Am J Surg Pathol 2014-03-06

...PIK3CA, homozygous deletion of FBXW7, and amplifications of CDK4, FGFR1, IGF1R, KDR, KIT, and MCL1. The frequency of GA ...

Cornen(Stéphanie),Guille(Arnaud),Adélaïde(... PLoS One 2014-09-08

...PIK3CA and TP53 were the most frequent mutated genes among the nine tested. In a meta-analysis of next-generation sequen...

Zhang(Zhimin),Xiao(Hualiang),Xie(Fei),Zhan... BMC Cancer 2014-10-30

...PIK3CA and PTEN mutations in PSCCE.,Clinical-pathological data and paraffin-embedded specimens were collected from 38 pa...

Yu(Qian-Qian),Wu(Hao),Huang(Xiang),Shen(Hu... Biomed Pharmacother 2014-11-17

...PIK3CA directly. PIK3CA downregulation by miR-1 mimics led to a significant reduction of phosphorylated Akt and survivin...

Pesson(Marine),Eymin(Béatrice),De La Grang... Mol Cancer 2014-09-08

...PIK3CA, PIK3R1-2, VEGFA-D and PIR, we engineered a dedicated gene chip with coverage of an average 185 probes per gene a...

Jin(Ying),Li(Yan),Pan(Lingya) Onco Targets Ther 2014-10-06

...PIK3CA and inactivation of PTEN, is involved in tumorigenesis of CCC. Targeting angiogenesis, the Met protooncogene path...

Kim(Dong Choon),Chung(Woo Jin),Lee(Jae-Ho)... APMIS 2014-11-03

...PIK3CA) or hepatitis B virus X (HBx) gene. Previous studies have examined the frequency of PIK3CA mutations in HCC, alth...

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