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MicroRNA-203 accelerates apoptosis in LPS-stimulated alveolar epithelial cell...

Ke(Xian-Fu),Fang(Jie),Wu(Xiao-Ning),Yu(Che... Biochem Biophys Res Commun 2014-11-04

...PIK3CA), a direct target of miR-203 identified by bioinformatics, thereby suppressing the PI3K/Akt pathway. Moreover, re...

mTOR co-targeting in cetuximab resistance in head and neck cancers harboring ...

Wang(Zhiyong),Martin(Daniel),Molinolo(Alfr... J Natl Cancer Inst 2014-11-14

...PIK3CA and RAS oncogenes. These cells and HNSCC cells harboring endogenous PIK3CA and RAS oncogenes were xenografted int...

CDKN2A(p16) and HRAS are frequently mutated in vulvar squamous cell carcinoma...

Trietsch(Marjolijn D),Spaans(Vivian M),ter... Gynecol Oncol 2014-12-22

...PIK3CA, PPP2R1A, PTEN, and TP53) using Sanger sequencing and mass spectrometry.,Mutations were detected in 7 genes. Of 1...

The mutational burdens and evolutionary ages of early gastric cancers are com...

Kim(Tae-Min),Jung(Seung-Hyun),Kim(Min Sung... J Pathol 2014-12-09

...PIK3CA, ARID1A, and KRAS) that were enriched in cancer-related pathways, including chromatin remodelling and tyrosine ki...

Oncogenic mutations are associated with histological subtypes but do not have...

Hu(Haichuan),Pan(Yunjian),Li(Yuan),Wang(Le... Onco Targets Ther 2014-08-25

...PIK3CA, ALK, and RET for oncogenic mutations/rearrangements, and a rereview of the IASLC/ATS/ERS classification was unde...

Hsp70 inhibition potentiates radicicol-induced cell death in anaplastic thyro...

Kim(Si Hyoung),Kang(Jun Goo),Kim(Chul Sik)... Anticancer Res 2014-11-11

...PIK3CA plasmid-transfected cells, compared to cells treated with radicicol-alone, cell viability increased and cellular ...

PIK3CA mutations are associated with lower rates of pathologic complete respo...

Loibl(Sibylle),von Minckwitz(Gunter),Schne... J Clin Oncol 2014-12-03

...PIK3CA mutation. Detection of a PIK3CA mutation was significantly associated with a lower pCR rate (19.4% with PIK3CA mu...

KRAS and PIK3CA mutation frequencies in patient-derived xenograft models of p...

Tignanelli(Christopher J),Herrera Loeza(Si... Am Surg 2014-11-03

...PIK3CA mutations. Fifteen of 37 (41%) CRC PDXs had KRAS mutations and three of 37 (8%) had PIK3CA mutations. Mutations w...

Tumor LINE-1 methylation level and microsatellite instability in relation to ...

Inamura(Kentaro),Yamauchi(Mai),Nishihara(R... J Natl Cancer Inst 2014-11-14

...PIK3CA mutations. Statistical tests (log-rank test, chi-square test, and likelihood ratio test) were two-sided.,In MSI-h...

Down Regulation of FOXO1 Promotes Cell Proliferation in Cervical Cancer.

Prasad(Shyam Babu),Yadav(Suresh Singh),Das... J Cancer 2014-08-26

...PIK3CA and AKT1; and down regulation of FOXO1. Lack of FOXO1 promoter methylation and inability of hypomethylating drug ...

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