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Pan-Cancer Bioinformatics-Guided Evaluation of San-Huang-Xie-Xin-Tang Identif...

Zuo(SY),Chou(YP),Hsu(TH),Chang(JG),Chan(WL... Pharmaceuticals (Basel) 2026-06-14

...PIK3CA, PIK3CB, KRAS, and RAF1, remained significantly associated with favorable prognostic alignment after multivariabl...

The Effect of Anti-Inflammatory Drugs on the Incidence of Colorectal Cancer.

Misiak(M),Maciejowska(A),Pałęga(M),Burek(R... Pharmaceutics 2026-05-23

...PIK3CA gene. Factors influencing the effectiveness of CRC treatment include molecular differences and tumor location. Co...

Synergistic Inhibition of Colorectal Cancer Growth by Combined PI3K and COX-2...

Nghiem(E),Tzamarot(A),Li(T),Huang(Z),Moham... Pharmaceutics 2026-05-30

...PIK3CA mutation status. In patient-derived organoid models, while synergy was seen in both organoids, growth of the PIK3...

Molecular Characterization of Hotspot Mutations in HER2, BRAF, KRAS, and PIK3...

Muramatsu(A),Nagashima(T),Ochiai(K),Ohnuma... Vet Sci 2026-06-18

...PIK3CA were analyzed in 20 surgically resected canine pulmonary adenocarcinomas and three canine pulmonary adenocarcinom...

Phase IB/II study of alpelisib combined with paclitaxel in patients with PIK3...

Kim(JW),Yoon(S),Ryu(MH),Lim(SH),Kim(ST),Ki... Oncologist 2026-07-08

...PIK3CA-altered metastatic or recurrent gastric cancer (GC). In phase IB, patients with advanced solid tumors received al...

Pan-cancer analysis identifies immunoproteasome as the predominant survival-a...

Lai(JI),Liu(CY),Tsai(YF),Huang(CC),Tseng(L... Transl Oncol 2026-09-00

...PIK3CA, KRAS, BRAF, TP53, and EGFR. High APM expression was associated with improved survival, particularly in CEN-posit...

Detection of mutant cancer-derived circRNAs in extracellular vesicles by roll...

Zaborowski(MP),Lai(CP),Sammarco(A),György(... Mol Ther Nucleic Acids 2026-09-08

...PIK3CA genes in EVs from cancer cells. We noticed that circRNAs in EVs undergo intense rolling circle amplification (RCA...

Pharmacovigilance Signal Detection and Mutually Exclusive Driver Mutations of...

Luo(Z),Shi(Y),Zhu(B),Huang(Q),Zhang(W),Shi... Hum Mutat None

...PIK3CA, AKT1, and PTEN alterations. Furthermore, scRNA-seq analysis demonstrated that GSK3B overexpression defines a hig...

Screening the Mechanism of Shikonin Against Renal Cell Carcinoma via Network ...

Gong(WW),Yang(Y),Wang(SM),Zha(X),Ruan(JH),... J Vis Exp 2026-06-12

...PIK3CA, PIK3CB, PIK3CD, PTPN11, and PIK3R1) were identified. Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Geno...

A phase II study of alpelisib and capecitabine in patients with previously tr...

Lim(AR),Kang(SY),Choi(MK),Lee(MA),Kim(JY),... Sci Rep 2026-06-29

...PIK3CA-mutant metastatic colorectal cancer who had progressed after standard chemotherapy. Patients received oral alpeli...

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