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TP53 BRCA1 CRISPR single-cell cancer

Huang(Lulu),Liu(Zhenfang),Deng(Donghong),T... Arch Med Sci 2014-06-24

We conducted a meta-analysis to dissect the association between PIK3CA mutations (exon 9 and exon 20) and resistance to ...

Bradford(Leslie S),Rauh-Hain(Alejandro),Cl... Gynecol Oncol 2014-06-12

...PIK3CA mutation was observed. Acute treatment with BKM led to a decrease in pAKT levels.,Independent of PIK3CA gene muta...

Wiegand(Kimberly C),Hennessy(Bryan T),Leun... BMC Cancer 2014-12-28

...PIK3CA mutations were characterized by MALDI-TOF mass spectrometry. SAM (Significance Analysis of Microarrays) was perfo...

Pecuchet(N),Bigot(F),Henni(M),Fabre(E) Rev Pneumol Clin 2014-12-04

...PIK3CA, DDR2 mutations. Some of these alterations are already elegible for dedicated targeted therapies within clinical ...

Gibault(L),Cazes(A),Narjoz(C),Blons(H) Rev Pneumol Clin 2014-12-04

...PIK3CA, ALK, ROS, RET…) have been identified as potential target of novel therapies, and molecular profiling has become ...

Guarneri(Valentina),Generali(Daniele Giuli... J Clin Oncol 2014-05-29

...PIK3CA mutation (objective response rate, 93% v 63% in PIK3CA wild type; P = .040).,The combination of letrozole-lapatin...

Sakai(Eiji),Ohata(Ken),Chiba(Hideyuki),Mat... Int J Cancer 2014-10-20

...PIK3CA, and immunostaining of TP53 and CTNNB1 as well as other clinicopathological factors were also evaluated. By hiera...

Song(Yongmei),Li(Lin),Ou(Yunwei),Gao(Zhibo... Nature 2014-06-16

...PIK3CA, NOTCH1, NFE2L2), and two have not previously been described in ESCC (ADAM29 and FAM135B). Notably, FAM135B is id...

Iwamoto(Shigeyoshi),Hazama(Shoichi),Kato(T... Anticancer Res 2014-06-15

...PIK3CA genotyping.,Tumors of 112 pre-registered patients were genotyped for KRAS, BRAF, and PIK3CA. The primary study en...

Schleifman(Erica B),Desai(Rupal),Spoerke(J... PLoS One 2014-10-13

...PIK3CA and AKT1 alterations or PTEN and Ki67 levels showed differences between primary and metastatic samples. We also s...

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