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TP53 BRCA1 CRISPR single-cell cancer

Janku(Filip),Hong(David S),Fu(Siqing),Piha... Cell Rep 2014-09-26

...PIK3CA or PTEN abnormalities, PIK3CA mutations were found in 9% (146/1,589), and PTEN loss and/or mutation was found in ...

Kuhn(Elisabetta),Ayhan(Ayse),Bahadirli-Tal... Am J Surg Pathol 2014-05-27

...PIK3CA (50%), CTNNB1 (30%), TP53 (30%), FBXW7 (20%), and PPP2R1A (20%). All somatic mutations detected in EMCs were also...

Shinmura(Kazuya),Kato(Hisami),Matsuura(Shu... Oncol Rep 2014-09-26

...PIK3CA and SOX2 amplifications. The above results suggest that an FGFR3 p.R248H mutation is involved in the carcinogenes...

Cui(Wenli),Cai(Ying),Wang(Weige),Liu(Zebin... J Transl Med 2014-09-05

...PIK3CA (P = 0.002) but also positively correlated with strong positive expression of pAKT (P = 0.026).,CNV of PIK3CA is ...

Ross(Jeffrey S),Wang(Kai),Rand(Janna V),Sh... Am J Surg Pathol 2014-03-06

...PIK3CA, homozygous deletion of FBXW7, and amplifications of CDK4, FGFR1, IGF1R, KDR, KIT, and MCL1. The frequency of GA ...

Ahls(Maria Gabriele),Niedergethmann(Marco)... Diagn Pathol 2014-09-04

...PIK3CA and GNAS. Altogether, histology, immunohistochemical expression profile (MUC1+, MUC6+, MUC2-, MUC5AC-, thrypsin-,...

Kang(Melissa),Shen(Xiang J),Kim(Sangmi),Ar... Cancer Biomark 2014-09-08

...PIK3CA mutations might contribute to the racial differences in CRC outcome.,DNA was extracted from tissue microarrays ma...

Shern(Jack F),Chen(Li),Chmielecki(Juliann)... Cancer Discov 2014-09-30

...PIK3CA, and CTNNB1, we found novel recurrent mutations in FBXW7 and BCOR, providing potential new avenues for therapeuti...

Cornen(Stéphanie),Guille(Arnaud),Adélaïde(... PLoS One 2014-09-08

...PIK3CA and TP53 were the most frequent mutated genes among the nine tested. In a meta-analysis of next-generation sequen...

Pesson(Marine),Eymin(Béatrice),De La Grang... Mol Cancer 2014-09-08

...PIK3CA, PIK3R1-2, VEGFA-D and PIR, we engineered a dedicated gene chip with coverage of an average 185 probes per gene a...

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