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Mutation incidence and coincidence in non small-cell lung cancer: meta-analys...

Dearden(S),Stevens(J),Wu(Y-L),Blowers(D) Ann Oncol 2014-05-14

...PIK3CA, and ErbB2. The mutMap highlighted mutation coincidences occurring in ≥5% of patients, including TP53 with KRAS o...

Oncogene mutational profile in nasopharyngeal carcinoma.

Zhang(Zi-Chen),Fu(Sha),Wang(Fang),Wang(Hai... Onco Targets Ther 2014-03-27

...PIK3CA mutations (4.9%), five NRAS mutations (4.1%), four KIT mutations (3.3%), two PDGFRA mutations (1.6%), two ABL mut...

Synergistic effects of targeted PI3K signaling inhibition and chemotherapy in...

Guo(Shang),Lopez-Marquez(Hector),Fan(Kenne... PLoS One 2014-11-17

...PIK3CA gene in 4 of 18 human liposarcoma patients (22%). No PIK3CA mutations were identified in benign lipomas. Western ...

Multigene profiling to identify alternative treatment options for glioblastom...

Tabone(Tania),Abuhusain(Hazem J),Nowak(Ann... J Clin Pathol 2014-08-15

...PIK3CA (n=5). Clinically actionable somatic mutations were detected in 24/35 (69%) patients.,This study demonstrates tha...

Genetic mechanisms in interval colon cancers.

Richter(James M),Pino(Maria Simona),Austin... Dig Dis Sci 2014-10-17

...PIK3CA oncogenes was similar between interval cancer cases and controls.,Interval colon cancers are not distinguished by...

Defined morphological criteria allow reliable diagnosis of colorectal serrate...

Rau(Tilman T),Agaimy(Abbas),Gehoff(Anastas... Virchows Arch 2014-07-29

...PIK3CA and the methylation status of MLH1. Gender, age and localisation were significantly associated with certain types...

Primary concomitant EGFR T790M mutation predicted worse prognosis in non-smal...

Li(Hang),Hu(Haichuan),Wang(Rui),Pan(Yunjia... Onco Targets Ther 2014-04-14

...PIK3CA (phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha), and EML4 (echinoderm microtubule assoc...

Immunohistochemical analysis of PDK1 expression in breast cancer.

Arsenic(Ruza) Diagn Pathol 2014-12-30

...PIK3CA mutation status.,Moderate or high expression of PDK1 was observed in 213 of the 241 cases (88%). There was no cor...

A GG allele of 3'-side AKT1 SNP is associated with decreased AKT1 activation ...

Wang(Xiaoting),Lin(Youdong),Lan(Fenghua),Y... J Cancer Res Clin Oncol 2014-09-02

...PIK3CA, PTEN, AKT1, and mTOR, were determined in 221 patients with stage T2 and T3 gastric cancer. Additionally, the act...

BRAF mutation predicts for poor outcomes after metastasectomy in patients wit...

Yaeger(Rona),Cercek(Andrea),Chou(Joanne F)... Cancer 2014-12-09

...PIK3CA (phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha) mutation frequency, and outcomes after ...

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