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Network based approach identifies miR-145-3p as a central regulatory hub asso...

Citarella(A),Petti(M),Besharat(ZM),Alfano(... J Pathol 2026-09-09

...PIK3CA, AKT1, and MAPK7. In MTC cells, simultaneous inhibition of miR-145-3p together with its top co-expressed miRNAs i...

Mechanism of Qilu Buxue granules in alleviating chemotherapy-induced leukopen...

Khan(MR),Akram(R),Luqman(A),Ullah(R),Ullah... J Ethnopharmacol 2026-09-12

...PIK3CA, and HRAS as core target proteins. GO and KEGG enrichment analysis revealed PI3K/AKT, JAK/STAT signaling, inflamm...

Association between HOMA-IR and coexisting MASLD and type 2 diabetes: Insight...

Heng(XP),Yang(LQ),Chen(QW),Jin(LX),Li(YW),... Ther Adv Endocrinol Metab 2026-00-00

...PIK3CA, and SRC as candidate hub targets and suggested candidate pathways related to PI3K-Akt, FOXO, and MAPK signaling....

Elucidating adverse drug reactions and underlying molecular mechanisms of ive...

Liu(B),Chen(X),Wang(Y),Zhang(H),Liang(X),G... Front Cell Infect Microbiol 2026-00-00

...PIK3CA, and HSPG2. KEGG enrichment analysis highlighted pathways related to parasitic diseases, leukocyte migration, and...

Single-center experience using reflex-targeted next-generation sequencing at ...

Pirlog(R),Hofman(V),Goffinet(S),Bontoux(C)... Virchows Arch 2026-04-00

...PIK3CA [9/108; (8.3%)], PTEN [(8/108 (7.4%)], and KRAS [6/108; (5.6%)]. The genes with the most frequent copy number var...

Structural Insights into the Development of Inhibitors Against Cancer-Specifi...

Liu(X),Chen(Y),Han(W),Chen(Y),Feng(W),Zhou... Annu Rev Pharmacol Toxicol 2026-01-00

...PIK3CA mutations (e.g., H1047R, E542K, and E545K), is a hallmark of many cancers. Advances in structural, biochemical, a...

Precision Medicine for Somatic Mutation-Driven Vascular Anomalies.

Xu(Y),Zhou(J),Lan(Y),Ji(Y) Br J Dermatol 2026-09-17

...PIK3CA mutations in lymphatic and venous malformations, KRAS/MAP2K1 mutations in arteriovenous malformations, and cerebr...

Post-CDK4/6 Inhibitor Therapeutic Approaches in Hormone Receptor-Positive, HE...

Al-Shamsi(HO),Abdelwahed(N),Abdelwahab(SI)... Diagnostics (Basel) 2026-06-10

...PIK3CA-mutated tumors, established the basis for biomarker-guided treatment in hormone receptor-positive, HER2-negative ...

Dauricine Mitigates Hypoxia Through Targeting ESR1, PIK3CA, and MTOR: A Netwo...

Ni(Z),Zhou(Z),Jia(F),Wu(J),Qiu(J),Yuan(K),... Curr Issues Mol Biol 2026-05-23

...PIK3CA, and MTOR, and by acting on key signaling pathways such as PI3K-Akt, MAPK, and mTOR. This study provides a theore...

SFTPB Expression Predicts Favorable Survival in Lung Adenocarcinoma but Poor ...

Kim(S),Hong(H),Lee(JH) Medicina (Kaunas) 2026-06-11

...PIK3CA (R = -0.143, p = 0.002), and TP53 (R = -0.101, p = 0.026). In contrast to AD, high SFTPB expression was significa...

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