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TP53 BRCA1 CRISPR single-cell cancer

Trejo(Christy L),Green(Shon),Marsh(Victori... Cancer Res 2014-01-07

...Pik3ca that allows conversion of the wild-type catalytic subunit of PIK3CA to mutationally activated PIK3CA(H1047R). Alt...

Jang(Sejin),Chun(Sung-Min),Hong(Seoung-Mo)... Mod Pathol 2014-12-24

...PIK3CA, CDKN2A, PTEN, and TP53 mutations were found with less than 5%. Overall mutation rate of intrahepatic cholangioca...

Ang(Daphne C),Warrick(Andrea L),Shilling(A... Mod Pathol 2014-12-24

...PIK3CA substitutions. PIK3CA point mutations were identified in 31/62 (50%) proliferative lesions (usual ductal hyperpla...

Mikhitarian(Kaidi),Pollen(Maressa),Zhao(Zh... Mod Pathol 2014-12-24

...PIK3CA, PTEN, and AKT1. A total of 52 ampullary carcinomas were identified, including 25 intestinal-type and 24 pancreat...

Shinmura(Kazuya),Kiyose(Shinichiro),Nagura... J Surg Oncol 2014-03-21

...PIK3CA, EPHB3, TNK2, PTK7, EGFR, MET, ERBB2, HCK, SRC, and AURKA) in gastric cancer (GC). This study aimed to determine ...

Bowcock(Anne M) Thorax 2014-05-27

...PIK3CA gene and evaluation of the number of copies of this gene gave very similar results to those from array comparativ...

Young(Geneva),Wang(Kai),He(Jie),Otto(Geoff... Cancer Cytopathol 2014-02-10

...PIK3CA, and KRAS. Eighty-seven genomic alterations were identified in the 23 pancreatic tumor FNAs (average, 3.8 genomic...

Yanus(Grigoriy A),Belyaeva(Anna V),Ivantso... Med Oncol 2014-04-17

...PIK3CA genes as well as for the microsatellite instability status. Comparison between high-resolution melting analysis, ...

Schneck(Helen),Blassl(Christina),Meier-Sti... Mol Oncol 2014-04-18

...PIK3CA variants E542K, E545G and E545A were not detected. Analysing the PIK3CA genotype of CTCs has clinical relevance w...

Kanagal-Shamanna(Rashmi),Portier(Bryce P),... Mod Pathol 2014-09-24

...PIK3CA, RET and TP53, deletions of EGFR and wild-type calls. Furthermore, next-generation sequencing detected variants i...

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