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TP53 BRCA1 CRISPR single-cell cancer

Zecchin(Davide),Boscaro(Valentina),Medico(... Mol Cancer Ther 2014-08-04

...PIK3CA oncogenes. Statistical analysis and clustering algorithms were applied to display similar drug response profiles ...

Welt(Anja),Tewes(Mitra),Aktas(Bahriye),O H... Breast Cancer Res Treat 2014-06-09

...PIK3CA mutations (23 %) and amplifications (2 %), loss of PTEN expression (13 %), and FGFR1 amplifications (8 %) were de...

Calderaro(Julien),Rebouissou(Sandra),de Ko... Int J Cancer 2014-05-15

...PIK3CA, KRAS, HRAS, NRAS and TP53 gene mutations. The series included 6 normal bladder urothelial samples and 129 UC (Ta...

Martin(Vittoria),Zanellato(Elena),Franzett... Histol Histopathol 2014-12-01

...PIK3CA hot-spots mutations using sequencing analysis in a cohort of 84 patients affected by SCAC.,Twenty-eight patients ...

Venanzi(Franco),Shifrin(Victor),Sherman(Mi... Oncotarget 2014-07-22

...PIK3CA and Her2) causes marked accumulation of p62. Based on this result, we hypothesized that p62 may be a feasible can...

Garcia-Carracedo(Dario),Turk(Andrew T),Fin... Clin Cancer Res 2014-08-26

...PIK3CA and AKT1 genes. PIK3CA and AKT1 gene amplifications and loss of heterozygosity at the PTEN locus were also evalua...

Kandula(Mahesh),Chennaboina(Kalyan Kumar),... Asian Pac J Cancer Prev 2014-12-31

...PIK3CA hotspots in exons 9 and 20 by direct sequencing of DNA obtained from biopsy samples. We have also analyzed expres...

He(Mao-Lin),Wu(Yang),Zhao(Jin-Min),Wang(Zh... Asian Pac J Cancer Prev 2014-12-31

...PIK3CA rs9866361 did not fit Hardy-Weinberg equilibrium (P < 0.05).,Genotype CC in locus PIK3CA rs7646409 may increase t...

Karapetis(Christos S),Jonker(Derek),Danesh... Clin Cancer Res 2014-10-06

...PIK3CA, and PTEN.,Available colorectal tumor samples were analyzed from the CO.17 study. BRAF mutations were identified ...

Marsh Durban(Victoria),Deuker(Marian M),Bo... J Clin Invest 2014-02-04

...PIK3CA), is rarely detected. Since PTEN has both PI3-lipid phosphatase-dependent and -independent tumor suppressor activ...

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