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Detection of cancer DNA in plasma of patients with early-stage breast cancer.

Beaver(Julia A),Jelovac(Danijela),Balukris... Clin Cancer Res 2015-02-09

...PIK3CA mutations, and DNA from these tumors and matched plasma were then analyzed for PIK3CA mutations using ddPCR.,Sequ...

Human papillomavirus-associated adenocarcinoma of the base of tongue: potenti...

Chang(Ann Margaret V),Nikiforova(Marina N)... Head Neck Pathol 2015-01-02

...PIK3CA exon 9 (p.E545K) and MET exon 2 (p.E168D) mutations were identified. No PIK3CA or MET amplification was identifie...

Discovery of colorectal cancer PIK3CA mutation as potential predictive biomar...

Ogino(S),Lochhead(P),Giovannucci(E),Meyerh... Oncogene 2014-07-22

...PIK3CA-mutated colorectal carcinoma, suggesting somatic PIK3CA mutation as a molecular biomarker that predicts response ...

Molecular pathogenesis of endometrial cancers in patients with Lynch syndrome...

Huang(Marilyn),Djordjevic(Bojana),Yates(Me... Cancer 2014-02-25

...PIK3CA); KRAS; AKT; LKB1; catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1); and phosphatase and tensin homo...

Dissecting the EGFR-PI3K-AKT pathway in oral cancer highlights the role of th...

Chang(Kwang-Yu),Tsai(Shan-Yin),Chen(Shang-... J Biomed Sci 2014-02-13

...PIK3CA revealed that 24.8% of the samples had alterations, and of EGFR showed that 49.0% had amplification. Direct seque...

Prognostic and putative predictive biomarkers of gastric cancer for personali...

Warneke(Viktoria S),Behrens(Hans-Michael),... Diagn Mol Pathol 2014-02-28

...PIK3CA genotype, microsatellite instability, mucin 1, mucin 2, mucin 5, and mucin 6, CD10, E-cadherin, β-catenin, and ly...

Towards the goal of personalized medicine in gastric cancer--time to move bey...

Lee(Jeeyun),Ou(Sai-Hong Ignatius) Discov Med 2014-04-18

...PIK3CA, BRAF) and gene rearrangement (ROS1, BRAF, HER2). Because of the low frequency of these potential driver mutation...

PIK3CA activating mutation in colorectal carcinoma: associations with molecul...

Rosty(Christophe),Young(Joanne P),Walsh(Mi... PLoS One 2014-01-21

...PIK3CA are present in 10 to 15% of colorectal carcinomas. We aimed to examine how PIK3CA mutations relate to other molec...

Lung adenocarcinoma biomarker incidence in Hispanic versus non-Hispanic white...

McQuitty(Elizabeth),Zhang(Wei),Hendrickson... Arch Pathol Lab Med 2014-05-01

...PIK3CA, AKT1 through AKT3, and PTEN with a custom Sequenom massARRAY assay (Sequenom, San Diego, California).,Mutations ...

Thymoma patients treated in a phase I clinic at MD Anderson Cancer Center: re...

Wheler(Jennifer),Hong(David),Swisher(Steph... Oncotarget 2014-05-12

...PIK3CA (1 of 12 tested; 8%); EGFR (1 of 13; 8%); RET (1 of 7; 14%); and AKT1 (1 of 7; 14%). Of two patients with PIK3CA ...

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