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Worenine attenuates pulmonary fibrosis potentially through modulation of PBK/...

Li(Y),Chen(N),Zhang(Y),Xiao(J),Zhao(S),Dua... Biomed Pharmacother 2026-09-05

...PIK3CA. Enrichment analyses indicated that worenine regulates pathways related to inflammation and cellular stress, incl...

Circulating Tumor DNA in Breast Cancer: A Liquid Biopsy Revolution for Non-In...

Obeagu(EI),Okafor(CJ) Breast Cancer (Auckl) 2026-00-00

...PIK3CA, ESR1, TP53, ERBB2, AKT1, and BRCA1/2. ctDNA has demonstrated particular utility in identifying minimal residual ...

CDState Resolves Malignant Cell Heterogeneity from Bulk Tumor RNA-Sequencing ...

Kraft(A),Yates(J),Barkmann(F),Boeva(V) Cancer Res 2026-07-30

...PIK3CA, SOX2, and SATB1 were identified as potential genetic drivers of malignant cell ITTH across cancer types. This st...

Biomarkers guiding fertility-sparing treatment in endometrial cancer.

Cokan(A),Zwimpfer(TA),Viveros-Carreño(D),G... Int J Gynecol Cancer 2026-06-27

...PIK3CA mutations may contribute to hormonal resistance, especially in combination. Ki-67 and L1 neuronal cell adhesion m...

[Somatic and immune profiling of chemotherapy-associated aplastic anemia: a c...

Zhang(YM),Zhou(YX),Zhuang(QL),Han(B) Zhonghua Xue Ye Xue Za Zhi 2026-05-14

...PIK3CA (FDR=0.049). Compared with patients with PAA, those with CAA had higher mutation frequencies in 213 genes, includ...

Oncogenic Signalling and Immune Checkpoint Crosstalk in Cancer: Emerging Targ...

Sekar(PKC),Veerabathiran(R) Curr Drug Targets 2026-08-18

...PIK3CA mutation, and AI-guided modelling frameworks offer structured approaches for translating these findings into clin...

The Molecular and Immunological Landscape in Nasopharyngeal Carcinoma (NPC) D...

Bracken-Clarke(D),Xue(E),Krause(H),Adeyelu... Cancer Med 2026-09-00

...PIK3CA (20.51%) and CYLD (10.53%)/NFKBIA (12.82%) mutations were enriched in SSTR2-Q1 versus -Q4. Tumor mutation burden ...

PIK3CA silencing restores anoikis sensitivity in endothelial cells.

Pereira(DMC),de Sousa Mesquita(AP),da Silv... Mol Biol Rep 2026-08-29

...PIK3CA gene silencing in anoikis-resistant endothelial cells. Consequently, these cells exhibited a reversal of malignan...

Terazosin Alleviates Apoptosis and Neuroinflammation in Cerebral Ischemia-rep...

Xie(L),Ping(Y),Zhao(J),Wu(Q),Huang(Y),Shan... Curr Neuropharmacol 2026-08-31

...PIK3CA, MTOR, and several other genes emerging as key hub genes. KEGG enrichment analysis revealed significant enrichmen...

Integrated UPLC-MS/MS profiling, computational prediction, and in vitro assay...

Deng(S),Longwei(F),Wang(X),Hu(S),Ye(Y) Nat Prod Res 2026-09-09

...PIK3CA, and KIT; all computational findings were hypothesis-generating. The extract inhibited mushroom tyrosinase (IC50 ...

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