主页文献库搜索
Ganetespib, a novel Hsp90 inhibitor in patients with KRAS mutated and wild ty...

Cercek(Andrea),Shia(Jinru),Gollub(Marc),Ch... Clin Colorectal Cancer 2015-07-23

...PIK3CA) mutational status was also determined.,Seventeen patients were treated (median age, 58; range, 44-79 years). No ...

Sequencing the head and neck cancer genome: implications for therapy.

Sun(Wenyue),Califano(Joseph A) Ann N Y Acad Sci 2015-03-05

...PIK3CA, and NOTCH1) and their corresponding pathways, with a particular focus on recent findings of Notch signaling path...

First-in-human phase I study of pictilisib (GDC-0941), a potent pan-class I p...

Sarker(Debashis),Ang(Joo Ern),Baird(Richar... Clin Cancer Res 2015-09-21

...PIK3CA amplification demonstrated partial response by RECIST and GCIG-CA125 criteria, respectively.,Pictilisib was safel...

PIK3CA mutational status in circulating tumor cells can change during disease...

Markou(Athina),Farkona(Sofia),Schiza(Chris... Clin Cancer Res 2015-07-09

...PIK3CA somatic mutations play a crucial role in therapy response. We investigated the presence of PIK3CA mutations in CT...

Programmed cell death 1 (PD-1) and its ligand (PD-L1) in common cancers and t...

Gatalica(Zoran),Snyder(Carrie),Maney(Todd)... Cancer Epidemiol Biomarkers... 2015-08-11

...PIK3CA; P = 0.002). In non-small cell lung cancer, PD-1/PD-L1 coexpression was identified in 8 cases (19%), which lacked...

Molecular characterization of serous ovarian carcinoma using a multigene next...

Ab Mutalib(Nurul-Syakima),Syafruddin(Saifu... BMC Res Notes 2015-07-06

...PIK3CA, STK11 and KIT) were exclusively altered in the tumor group. TP53 alterations were present in all the tumors but ...

Convergent loss of PTEN leads to clinical resistance to a PI(3)Kα inhibitor.

Juric(Dejan),Castel(Pau),Griffith(Malachi)... Nature 2015-02-27

...PIK3CA (phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha, PI(3)Kα) mutation. The patient was trea...

Molecular profiling of endometrial carcinoma precursor, primary and metastati...

Berg(Anna),Hoivik(Erling A),Mjøs(Siv),Hols... Oncotarget 2015-11-27

...PIK3CA mutations, PTEN loss, PI3K and KRAS activation are early events in endometrial carcinogenesis. Molecular changes ...

Basaloid carcinoma of the pancreas--clinicopathological presentation and onco...

Szasz(A Marcell),Szirtes(Ildiko),Tihanyi(B... Virchows Arch 2015-04-10

...PIK3CA, KRAS, and TP53 genes as drivers and variants of the FGFR3, PDGFRA, KIT, KDR, EGFR, RET, and ATM genes. The tumor...

Exploiting high-throughput cell line drug screening studies to identify candi...

Nichols(Anthony C),Black(Morgan),Yoo(John)... BMC Pharmacol Toxicol 2015-08-04

...PIK3CA mutant tumors. PIK3CA mutations may represent a predictive biomarker for response to PI3K inhibitors. A large-sca...

上一页 162 163 164 165 166 167 168 169 170 下一页 166 / 共 353

联系地址

山东省济南市章丘区文博路2号

齐鲁师范学院 genelibs生信实验室

山东省济南市高新区舜华路750号

大学科技园北区F座4单元2楼

电话: 0531-88819269

微信公众号

关注微信订阅号,实时查看信息,关注医学生物学动态。


商务邮箱

E-mail: product@genelibs.com