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TP53 BRCA1 CRISPR single-cell cancer

Wu(Chia-Yen C),Carpenter(Eileen S),Takeuch... Gastroenterology 2015-02-04

...Pik3ca), p110β (Pik3cb), or RAC1 (Rac1). Pancreatitis was induced with 5 daily intraperitoneal injections of cerulein. P...

Nussinov(Ruth),Jang(Hyunbum),Tsai(Chung-Jung) Oncotarget 2015-08-06

...PIK3CA p110α and p85, and the non-hotspot AKT1 mutants conferring constitutive membrane localization.

Lange(Falko),Franz(Benjamin),Maletzki(Clau... Biomed Res Int 2015-07-02

...PIK3CA, and TP53 mutations. Regorafenib action was associated with broad-range inhibitory effects at the level of gene e...

Mafficini(Andrea),Amato(Eliana),Fassan(Mat... PLoS One 2015-12-15

...PIK3CA, KRAS, and BRAF mutations were validated by conventional Sanger sequencing.,TM-NGS yielded overlapping results on...

Kalikaki(Aristea),Politaki(Helen),Souglako... PLoS One 2015-05-26

...PIK3CA and BRAF wild type primary tumors and 14 KRAS mutant tumors. CTCs were detected in 65% of specimens obtained from...

Yuen(Jessie Wai-Fong),Chung(Grace Tin-Yun)... PLoS One 2015-12-07

...PIK3CA amplification, we examined the role of INPP4B, a negative regulator of the PI3K/AKT signaling pathway in the deve...

Schneeweiss(Andreas),Chia(Stephen),Hegg(Ro... Breast Cancer Res 2015-06-22

...PIK3CA) by qRT-PCR, immunohistochemistry (IHC), fluorescence in situ hybridization (FISH), enzyme-linked immunosorbent a...

Couraud(Sébastien),Vaca-Paniagua(Felipe),V... Clin Cancer Res 2015-07-07

...PIK3CA) were identified, of which 26 were detected in cfDNA. Sensitivity of the test was 58% (95% confidence interval, 4...

Boland(Jennifer M),Wampfler(Jason A),Jang(... Am J Surg Pathol 2015-01-06

...PIK3CA. Overall, 53 of 763 cases (7%) were SRC⁺. In the 2006 to 2007 "all comer" cohort, 9% were SRC⁺. In the never-smok...

Song(Eun-Kee),Tai(W M),Messersmith(Wells A... Int J Cancer 2015-04-16

...PIK3CA gene. The underlying antitumor mechanisms of cabozantinib consisted of inhibition of angiogenesis and Akt activat...

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