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TP53 BRCA1 CRISPR single-cell cancer

Yea(Sung Su),So(Lomon),Mallya(Sharmila),Le... PLoS One 2015-01-29

...PIK3CA) is frequently mutated in human cancer. However, little is known about the function of p110α in lymphocyte popula...

Theeler(Brett J),Ellezam(Benjamin),Yust-Ka... J Neurol 2015-07-28

...PIK3CA mutation) were found in these tumors. All five patients received bevacizumab-containing regimens at tumor recurre...

Guo(Wenjie),Sun(Yang),Liu(Wen),Wu(Xingxin)... Autophagy 2015-05-11

...PIK3CA-AKT1-MTOR-RPS6KB1 pathway accounted for Andro-induced autophagy. Finally, Andro-driven inhibition of the NLRP3 in...

Zhu(Kunli),Yan(Hongjiang),Wang(Renben),Zhu... Med Oncol 2015-07-24

The objective was to evaluate DNA mutations of KRAS, BRAF, and PIK3CA and their clinicopathological correlations with co...

Zhu(Andrew X),Borger(Darrell R),Kim(Yuhree... Ann Surg Oncol 2015-06-16

...PIK3CA (4.3 %), NRAS (3.1 %), TP53 (2.5 %), MAP2K1 (1.9 %), CTNNB1 (0.6 %), and PTEN (0.6 %). Among patients with an IDH...

Gruel(Nadège),Benhamo(Vanessa),Bhalshankar... Breast Cancer Res 2015-04-16

...PIK3CA (n=41) sequencing in a series of IMPCs were performed. A subset of cases was also analysed with whole-exome seque...

Simbolo(Michele),Fassan(Matteo),Ruzzenente... Oncotarget 2015-02-19

...PIK3CA (7%). IDH1/2 (p=0.0005) and BAP1 (p=0.0097) mutations were characteristic of ICC, while KRAS (p=0.0019) and TP53 ...

Chen(Ying),McGee(Jeremy),Chen(Xianming),Do... PLoS One 2015-01-19

...PIK3CA. Wild-type KRAS was amplified in several cancer types, and KRAS-amplified cancer cell lines were most sensitive t...

Gadducci(Angiolo),Lanfredini(Nora),Tana(Ro... Gynecol Endocrinol 2015-05-14

...PIK3CA in 20-40% and of ARID1 in 15-75% of the cases. Whereas estrogen receptors and progesterone receptors are quite al...

Cohen(Ana S A),Townsend(Katelin N),Xiang(Q... Am J Med Genet A 2015-04-20

...PIK3CA, which was absent in blood. This report expands the phenotypic spectrum of mosaic PIK3CA mutations.

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