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TP53 BRCA1 CRISPR single-cell cancer

Seiwert(Tanguy Y),Zuo(Zhixiang),Keck(Micha... Clin Cancer Res 2015-09-22

...PIK3CA, and NOTCH genes. HPV-positive tumors showed unique mutations in DDX3X, FGFR2/3 and aberrations in PIK3CA, KRAS, ...

Xu(Binghe),Guan(Zhongzhen),Shen(Zhenzhou),... Breast Cancer Res 2015-06-22

Phosphatidylinositol 3-kinase (PI3K) pathway deregulation (that is PIK3CA mutations and/or phosphatase and tensin homolo...

Er(Tze-Kiong),Chen(Chih-Chieh),Bujanda(Lui... Biomed Res Int 2015-03-12

...PIK3CA, and PTEN status could be the right strategy to select patients who are likely to respond to anti-EGFR therapies....

Li(Tingting),Liao(Xiaoyun),Lochhead(Paul),... Ann Surg Oncol 2015-07-24

...PIK3CA, microsatellite instability, CpG island methylator phenotype (CIMP), LINE-1 methylation, and expression of phosph...

Toschi(Luca),Finocchiaro(Giovanna),Nguyen(... PLoS One 2015-05-29

...PIK3CA, FGFR1 and BRF2 gene gain in patients with surgically resected non-small cell lung cancer (NSCLC).,SOX2, PIK3CA, ...

Kumari(Niraj),Corless(Christopher L),Warri... Indian J Pathol Microbiol 2015-04-07

...PIK3CA (two cases), and KRAS (one case). Six of these cases were well differentiated but of eight of them belonged to st...

Ahn(TaeJin),Park(Taesung) Biomed Res Int 2015-01-05

...PIK3CA, and RB1. In addition, out of 15,819 genes considered in breast cancer, our approach identified mutational events...

McCubrey(James A),Davis(Nicole M),Abrams(S... Adv Biol Regul 2015-05-19

...PIK3CA, RB, P16INK1 and various miRs as well some drugs which are showing promise in targeting CICs. In addition, the co...

Henderson(Stephen),Chakravarthy(Ankur),Su(... Cell Rep 2015-04-16

...PIK3CA gene across multiple cancers. Our findings implicate APOBEC activity as a key driver of PIK3CA mutagenesis and HP...

Wheler(Jennifer J),Moulder(Stacy L),Naing(... Oncotarget 2015-01-23

...PIK3CA (n=3) and AKT1 (n=1) or PTEN loss (n=3). All three responders (CR (n = 1); PR (n=2)) who had next generation sequ...

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