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Constitutive AKT activation in follicular lymphoma.

Yahiaoui(Ouardia I),Nunès(Jacques A),Casta... BMC Cancer 2015-04-07

...PIK3CA somatic mutations in exon 9 and 20 using direct sequencing. The same samples were analyzed using western blotting...

Mutational analysis of PI3K/AKT signaling pathway in tamoxifen exemestane adj...

Sabine(Vicky S),Crozier(Cheryl),Brookes(Ca... J Clin Oncol 2015-02-09

...PIK3CAx10, AKT1x1, KRASx5, HRASx3, NRASx2 and BRAFx4).,PIK3CA mutations were frequent (39.8%), whereas RAS/RAF mutations...

Molecular spectrum of KRAS, BRAF, and PIK3CA gene mutation: determination of ...

Bisht(Swati),Ahmad(Firoz),Sawaimoon(Satyak... Med Oncol 2015-04-02

...PIK3CA mutation using direct sequencing in 204 samples. The frequency of KRAS, BRAF, and PIK3CA mutations was 23.5, 9.8,...

Prenatal diagnosis of CLOVES syndrome confirmed by detection of a mosaic PIK3...

Emrick(Lisa T),Murphy(Lauren),Shamshirsaz(... Am J Med Genet A 2015-06-04

...PIK3CA, a gene involved in the receptor tyrosine kinase phosphatidylinositol 3-kinase (PI3)-AKT growth-signaling pathway...

Small bowel adenocarcinomas complicating Crohn's disease are associated with ...

Svrcek(Magali),Piton(Gael),Cosnes(Jacques)... Inflamm Bowel Dis 2015-05-28

...PIK3CA mutations.,All neoplastic lesions, except 1 lesion, were found in inflamed mucosal areas. Dysplasia was found in ...

Current approaches for predicting a lack of response to anti-EGFR therapy in ...

Er(Tze-Kiong),Chen(Chih-Chieh),Bujanda(Lui... Biomed Res Int 2015-03-12

...PIK3CA, and PTEN status could be the right strategy to select patients who are likely to respond to anti-EGFR therapies....

Deciphering combinations of PI3K/AKT/mTOR pathway drugs augmenting anti-angio...

Sasore(Temitope),Kennedy(Breandán) PLoS One 2015-05-11

...pik3ca, pik3r1, mtor and akt1) in zebrafish trunks from 6 hours post fertilisation (hpf) and in eyes from 2 days post fe...

[Research status on molecular targeted therapy for squamous-cell lung cancer]...

Li(Yanan),Zhou(Yunzhi),Wang(Hongwu) Zhongguo Fei Ai Za Zhi 2015-04-02

...PIK3CA), fibroblast growth factor receptor 1 (FGFR1), discoidin domain receptor 2 (DDR2), phosphatase and tensin homolog...

RNA-seq of 272 gliomas revealed a novel, recurrent PTPRZ1-MET fusion transcri...

Bao(Zhao-Shi),Chen(Hui-Min),Yang(Ming-Yu),... Genome Res 2015-07-20

...PIK3CA signaling and lowered expression of genes that suppressed RB1 or TP53 function. Expression of the ZM fusion was m...

Recurrent RAS and PIK3CA mutations in Erdheim-Chester disease.

Emile(Jean-François),Diamond(Eli L),Hélias... Blood 2015-01-05

...PIK3CA, and AKT1 mutational analysis in BRAF wild-type patients. Forty-six of 80 (57.5%) of patients were BRAFV600E-muta...

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