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TP53 BRCA1 CRISPR single-cell cancer

Ye(X-F),Wang(J),Shi(W-T),He(J) Br J Cancer 2015-01-26

...PIK3CA gene but not for those with wild-type PIK3CA.,Based on current evidence, the use of aspirin after diagnosis does ...

Rothé(F),Laes(J-F),Lambrechts(D),Smeets(D)... Ann Oncol 2015-06-11

...PIK3CA, PTEN, AKT1 or IDH2 gene. When plasma samples were analyzed, 12 of 17 (71%, 95% CI: 44-90%) patients had ≥1 mutat...

Lopez(Salvatore),Schwab(Carlton L),Cocco(E... Gynecol Oncol 2015-01-29

...PIK3CA, against primary uterine serous carcinomas (USC) harboring PIK3CA mutations and HER2/neu gene amplification.,Sens...

Pang(Bo),Cheng(Shi),Sun(Shi-Peng),An(Cheng... Sci Rep 2015-10-16

...PIK3CA mutations and ER/PR expression and the prognostic role of PIK3CA mutations in BCa patients, and in particular, HR...

Shukuya(Takehito),Serizawa(Masakuni),Watan... Lung Cancer 2015-06-10

...PIK3CA, NRAS, MEK1, AKT1, PTEN, and HER2 and amplifications in EGFR, MET, PIK3CA, FGFR1, and FGFR2. In addition, 21 pati...

Zardavas(Dimitrios),Phillips(Wayne A),Loi(... Breast Cancer Res 2015-04-16

...PIK3CA mutations and their potential implications. Prospective clinical trials stratifying by PIK3CA genotype will be ne...

Mazumdar(Tuhina),Byers(Lauren A),Ng(Patric... Mol Cancer Ther 2015-11-10

...PIK3CA mutations were sensitive to pathway inhibitors, whereas amplification status did not predict sensitivity. While w...

Ranzani(Marco),Annunziato(Stefano),Calabri... Mol Ther 2015-10-22

...PIK3CA and PIK3CB, by showing that their forced expression confers resistance to lapatinib in vitro and found that their...

Huang(Hsien-Neng),Lin(Ming-Chieh),Tseng(Li... Histopathology 2015-11-05

...PIK3CA. High levels of microsatellite instability (MSI-H) were present in one of 26 OVEMs, 12 of 42 EMCAs, and four of 1...

Umemura(Shigeki),Mimaki(Sachiyo),Makinoshi... J Thorac Oncol 2015-05-12

...PIK3CA, 6%; PTEN, 4%; AKT2, 9%; AKT3, 4%; RICTOR, 9%; and mTOR, 4%. Furthermore, the individual changes in this pathway ...

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