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Unique molecular signatures as a hallmark of patients with metastatic breast ...

Wheler(Jennifer J),Parker(Barbara A),Lee(J... Oncotarget 2015-02-19

...PIK3CA, CCND1, MYC, HER2 (ERBB2), MCL1, PTEN, FGFR1, GATA3, NF1, PIK3R1, BRCA2, EGFR, IRS2, CDH1, CDKN2A, FGF19, FGF3 an...

Characterization of breast cancers with PI3K mutations in an academic practic...

Abramson(Vandana G),Cooper Lloyd(M),Ballin... Breast Cancer Res Treat 2015-11-12

...PIK3CA mutation was found in 25 % of tumors tested. Patients with PIK3CA mutations were significantly more likely to exp...

The mutational spectrum of squamous-cell carcinoma of the head and neck: targ...

Mountzios(G),Rampias(T),Psyrri(A) Ann Oncol 2015-06-11

...PIK3CA, CCND1 and HRAS) as driver genetic events in SCCHN neoplastic transformation. More recently, comprehensive data f...

Cancers of the upper gastro-intestinal tract: a review of somatic mutation di...

Abedi-Ardekani(Behnoush),Hainaut(Pierre) Arch Iran Med 2015-01-16

...PIK3CA. Another three genes, NFE2L2, PTCH1 and NOTCH1, are mutated in ESCC only. Conversely, genes of the RAS family and...

Activating BRAF and PIK3CA mutations cooperate to promote anaplastic thyroid ...

Charles(Roch-Philippe),Silva(Jillian),Iezz... Mol Cancer Res 2015-04-21

...PIK3CA to demonstrate that, although mutationally activated PIK3CA(H1047R) is unable to drive transformation on its own,...

Clinical delineation and natural history of the PIK3CA-related overgrowth spe...

Keppler-Noreuil(Kim M),Sapp(Julie C),Lindh... Am J Med Genet A 2015-08-18

...PIK3CA mutations include fibroadipose overgrowth (FAO), Hemihyperplasia multiple Lipomatosis (HHML), Congenital Lipomato...

Epithelial mesenchymal transition in early invasive breast cancer: an immunoh...

Aleskandarany(Mohammed A),Negm(Ola H),Gree... Breast Cancer Res Treat 2015-11-12

...PIK3CA, pAkt, and others. Reverse phase protein array (RPPA) was performed for quantitative analysis of proteins extract...

FGFR1 mRNA and protein expression, not gene copy number, predict FGFR TKI sen...

Wynes(Murry W),Hinz(Trista K),Gao(Dexiang)... Clin Cancer Res 2015-10-15

...PIK3CA mutations.,FGFR1 dependency is frequent across various lung cancer histologies, and FGFR1 mRNA may serve as a bet...

Clinicopathological features and prognostic roles of KRAS, BRAF, PIK3CA and N...

Takahashi(Naoki),Yamada(Yasuhide),Taniguch... BMC Res Notes 2015-01-15

...PIK3CA mutations by direct-sequencing. We retrospectively investigated the clinicopathological features of these mutatio...

Mutational context and diverse clonal development in early and late bladder c...

Nordentoft(Iver),Lamy(Philippe),Birkenkamp... Cell Rep 2015-08-21

...Pik3ca/Kdm6a mutations and may reflect the field-disease mutations shared among later tumors.

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