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TP53 BRCA1 CRISPR single-cell cancer

Iwasaki(Takeshi),Matsushita(Michiko),Nonak... Hum Pathol 2015-03-20

...PIK3CA mutations were observed more frequently in MCPyV-positive MCCs (6/36 [17%] vs 2/20 [10%]). These results suggest ...

Castaneda(Carlos A),Lopez-Ilasaca(Marco),P... Hematol Oncol Stem Cell The... 2015-08-19

...PIK3CA mutations were confirmed in a second independent run of sample testing.,PIK3CA mutations were present in 21/134 c...

Lipsyc(Marla),Yaeger(Rona) J Gastrointest Oncol 2015-12-23

...PIK3CA, and NRAS oncogenes and clinical outcomes and metastatic patterns of mCRC. The presence of a KRAS mutation is ass...

Botezatu(Irina V),Nechaeva(Irina O),Stroga... Data Brief 2015-12-24

...PIK3CA gene ("hot spots" in exons 9 and 20) are found in many human cancers, and their presence can determine prognosis ...

Tang(Jie-Ting),Wang(Zhen-Hua),Fang(Jing-Yuan) Onco Targets Ther 2015-11-25

...PIK3CA-mutation status.,LINE-1 hypomethylation is a potential biomarker for risk of CRC and associated with various clin...

Arsenic(Ruza),Treue(Denise),Lehmann(Annika... BMC Clin Pathol 2015-11-20

...PIK3CA, is one of the most frequently mutated genes in breast cancer, and the mutation status of PIK3CA has clinical rel...

Zheng(Shanbo),Pan(Yunjian),Wang(Rui),Li(Yu... Onco Targets Ther 2015-11-03

...PIK3CA, NFE2L2, and FGFR fusion genes. Clinical characteristics, including age, sex, smoking status, stage, relapse-free...

Munkley(Jennifer),Livermore(Karen E),McClu... Oncoscience 2015-10-27

...PIK3CA p110α catalytic subunit is also indirectly regulated by androgens at the protein level. We show that PIK3R1 mRNA ...

Zhang(L-H),Yin(A-A),Cheng(J-X),Huang(H-Y),... Oncogene 2015-04-10

...PIK3CA promoter via its PHD-Bromo domain to activate the transcription of PIK3CA gene, thus enhancing phosphatidylinosit...

Beelen(Karin),Opdam(Mark),Severson(Tesa M)... Breast Cancer Res 2015-04-16

...PIK3CA mutations (both exon 9 and exon 20) were associated with low tumor grade. An enrichment of PIK3CA exon 20 mutatio...

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